Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that hair-follicle-associated-pluripotent (HAP) stem cells can be cryopreserved for future use in nerve and spinal cord repair, with human trials being planned.

In this study, exposure to m-Aminophenol in human keratinocytes altered the expression of thousands of genes involved in inflammation and stress responses, suggesting potential biomarkers for MAP-induced skin toxicity.

This study found significant upregulation of IDO-1 and IDO-2 in human basal cell carcinomas, suggesting that IDO production may confer immune privilege characteristics to the tumors, potentially impacting their growth.

This review discusses the growth factors produced by adipose tissue-derived stem cells that are associated with hair growth stimulation and reports no new clinical findings.

This study identified that bacterially-induced metabolic changes in keratinocytes enhance skin and hair follicle regeneration, suggesting that modifying skin microbiome interactions may improve wound healing.

This study demonstrated that a ligand-independent action of the vitamin D receptor significantly affects keratinocyte behavior in hair follicles and skin, pointing to its crucial role in maintaining normal hair and skin structures in rats.

In this study, Myrtus communis leaf extract significantly reduced IL-1α expression and increased VEGF expression in human keratinocytes, which the researchers suggest may be linked to its traditional use in treating hair loss and wound healing. Further investigation is needed to clarify its mechanisms.

In this study, exposure to Myrtus communis leaf extract significantly reduced IL-1α expression and increased VEGF expression in human keratinocytes, which may relate to its traditional use for hair loss and wound healing; further research is necessary to understand its mechanisms.

In this study, human bone marrow mesenchymal stem cell-derived exosomes significantly accelerated cutaneous wound healing in rats by modulating the TGF-β/Smad signaling pathway.

This study found that basal cell carcinoma exhibits altered expression patterns of CD10, p63, BCL-2, and EMA proteins compared to normal skin, with notable differences in staining and reactivity.

In this study, predominant scalp bacteria, such as Cutibacterium acnes and Pseudomonas lini, were found to influence the expression of genes related to scalp and hair health in keratinocytes, potentially affecting scalp repair and hair growth.

This study found that implanting hair-follicle-associated pluripotent stem cell sheets in mice significantly accelerated wound closure and reduced scar formation compared to non-implanted controls.

This review highlights the role of epidermal tissue-resident memory T (T RM) cells in human skin, showing their involvement in immune surveillance and regulation within the epidermis, and suggesting their importance in understanding skin diseases like HIV infection and vitiligo.

In this study, researchers observed elevated levels of epidermal γδ T cells, keratinocytes, and an upregulation of the BST2 gene among immune cells in C3H/HeJ mice with alopecia areata, suggesting a potential role in disease pathogenesis.

This study explored how T cells interact with hair follicles in primary cicatricial alopecias by using spatial transcriptomics across mice, dogs, and human samples, revealing specific communication pathways and potential drug targets like CFD and S100A8/9 for future therapeutic research.

This study reports that in mice, CD11b+ myeloid cells can convert into epithelial cells, contributing to skin wound repair and hair follicle regeneration.

This study found that schizophrenia-derived neurons exhibited impaired differentiation and mitochondrial dysfunction, suggesting a potential link between these factors and neurodevelopmental processes in schizophrenia.

In this study, the immunohistochemical and lectin binding profiles of basal cell carcinoma closely resembled those of the outer root sheath of vellus hair follicles, suggesting a potential histochemical relationship.

This study found that NGAL expression in embryonic skin is spatio-temporally regulated and strongly induced in adult skin conditions with dysregulated differentiation, suggesting a role in epithelial differentiation pathways.

This review discusses the role of stress mediators in skin diseases and reports no new clinical results; the authors suggest further research in skin psychoneuroimmunology.

This review discusses the paracrine effects of adipose tissue-derived stem cells on surrounding cells and tissues, noting their potential therapeutic benefits, but reports no new clinical results.

This review discusses the biological features and clinical applications of epidermal stem cells in wound healing and tissue regeneration, emphasizing the need for further understanding of their mechanisms.

This research observed that dermal papilla cells have the potential to regenerate hair bulbs under preferred environmental conditions when associated with dermal sheath cells or exposed to specific growth factors.

This study found that the absence of unliganded vitamin D receptor significantly impairs cWnt and hedgehog signaling pathways necessary for hair cycle initiation in VDR-null mice.

In this study using mice with specific gene knockouts, both farnesyltransferase and geranylgeranyltransferase-I were found to be essential for the proliferation and survival of skin keratinocytes.

In this study, l-Ascorbic acid 2-phosphate was found to stimulate hair follicle growth in vitro by promoting IGF-1 expression via the PI3K pathway.

This study found that CD34+ cells from adipose tissue may enhance hair morphogenesis and participate in blood vessel formation in reconstituted skin tissues of mice.

This study found that the spermidine analog N1-methylspermidine prolonged hair follicle growth and decreased inflammation and oxidative stress in cultured hair follicles, suggesting potential relevance for treating inflammatory scalp diseases.

This study examined the expression patterns of various cytokeratins in the outer root sheath of human anagen hair follicles, noting distinct differentiation patterns and localization of keratin markers.

This study reported that minoxidil affects the physiology of cultured endothelial cells, including reversible suspension of cell proliferation and dose-dependent influence on cell morphology, without significantly altering protein synthesis or inhibiting cell migration.