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Activating Notch signaling can kill basal cell carcinoma cells.

Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.

Lacking cyclin D3 reduces skin cancer growth without affecting normal skin cell growth.

People with denser forearm hair have a higher risk of certain skin cancers.

Basal cell carcinomas may differentiate similarly to hair follicles and could be influenced by hair cycle-related treatments.

MPA increases cancer spread by boosting Eph A2 activity.

Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.

Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.

A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.

ILK is essential for skin development, pigmentation, and healing.

Ingenol mebutate gel changes gene expression related to skin development and immune response in actinic keratosis.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

The gene Prss53 affects hair shape and bone development in rabbits.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.

The meeting highlighted the genetic basis of female pattern hair loss and various skin health insights.

Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.

ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.

Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.

Hair follicle cells resist turning into skin cells.

A woman had a severe skin reaction from the drug imiquimod, used for skin cancer, highlighting the need for awareness of rare but serious side effects.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.