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The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Different hair care practices and conditions affect African American hair and scalp health, requiring specialized knowledge for treatment.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.

Phosphatidic acid may help hair grow by affecting cell growth pathways.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Plant-based ingredients are effective and safe for modern skincare products.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.

Anthralin is effective for psoriasis and alopecia with minimal systemic side effects but can irritate the skin.

Signaling pathways are crucial for hair growth in goats.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.

The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

A gene deletion causes the "hairless" trait in Iffa Credo rats.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

CD34 marks potential stem cells in dog hair follicles.

Graying hair happens due to aging and might be delayed by new treatments.

Quick treatment of hair disorders in teenage girls is important because of the emotional effects.

Chemical treatments and daily stresses damage hair, especially the cuticle layer.

Certain zinc transporters are essential for healthy skin and managing zinc in the body could help treat skin problems.

Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.

Treating excessive hair in women requires a holistic approach, including medical, aesthetic, and emotional support.

Nickel, cobalt, balsam of Peru, fragrance mix, carba mix, and propylene glycol are common allergens causing scalp contact dermatitis.