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RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

The gene KAP22-1 affects wool yield and fiber shape in sheep.

The KRTAP21-1 gene affects wool yield and can help improve wool production.

The KRTAP7-1 gene is very similar across different cattle and yak breeds and likely plays a role in hair strength and shape.

Researchers mapped and categorized specific keratin-associated protein genes on human chromosome 21q22.1.

Genetic variations in hair keratin proteins exist but don't significantly affect hair structure.

Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.

Sheep have a unique gene, KAP8-2, that humans don't have, which may affect wool properties.

High wool density in Rex rabbits is linked to specific gene activity affecting hair follicle development.

FGF-5 promotes Cashmere goat hair growth by increasing keratin genes and reducing certain LncRNA and target genes.

Certain gene variations are linked to the thickness of cashmere goat hair.

Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.

Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.

Runx1 helps control the KAP5 gene in human hair follicles.

The keratin network in mouse skin changes during cornification and affects the skin's protective barrier.

The Foxn1 gene is essential for normal nail and hair development.

The document concludes that recent research has improved understanding of skin diseases and the balance between cell growth and differentiation in the epidermis.

Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

Epidermolytic ichthyosis can be inherited in a semidominant way with mild symptoms in carriers.

The study found that genetic differences related to hair growth and other traits help cashmere goats adapt to high-altitude environments.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

Certain gene mutations are linked to wool quality in sheep and could help in breeding for better wool.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

The boy's severe skin disorder is caused by two new mutations in his TGM1 gene.

Keratin-associated proteins have ancient origins and were used for different purposes before being adapted for hair in mammals.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

The KRTAP21-2 gene affects wool length and quality in sheep.

Different androgen concentrations affect wool-related gene expression differently in Hetian and Karakul sheep breeds.

The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.