July 2026 in “Journal of the American Academy of Dermatology” JAK inhibitors are generally safe for treating alopecia areata.
June 2026 in “Serbian Journal of Dermatology and Venerology” This report highlights that oral Janus kinase inhibitors, including baricitinib, ritlecitinib, deuruxolitinib, and brepocitinib, show promise for treating alopecia areata by promoting substantial hair regrowth with mild-to-moderate side effects, positioning them as a favorable alternative to corticosteroids.
1 citations
,
November 2017 in “JFL : Jurnal Farmasi Lampung” In this study, researchers found that hair tonic formulations containing Nothopanax scutellarium extract enhanced hair growth in male rabbits over 21 days, with the 25% concentration showing comparable effects to a minoxidil-based positive control.
September 2016 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that jujube seed oil significantly increased the number of hair follicles in BALB/c mice compared to controls, suggesting potential benefits for hair growth.
February 2005 in “Journal of the American Academy of Dermatology” July 2023 in “JAAD Case Reports” June 2025 in “Revista Foco” This review assessed randomised clinical trials on the efficacy and safety of topical and systemic JAK inhibitors for alopecia areata, finding significant hair coverage improvement with ritlecitinibe and baricitinibe, though prolonged treatment is often needed to maintain results.
November 2017 in “Asian journal of pharmaceutical and clinical research” This study predicted that 6-hydroxy genistein, coreximine, and scoulerine from Dadap leaves may act as anti-alopecia agents by interacting with JAK2, but further in-vivo testing is needed.
September 2023 in “British Journal of Dermatology” In this study, researchers found that patients with severe alopecia areata show varied regrowth timelines with baricitinib, and those with the most severe cases may still experience delayed but eventual improvement.
2 citations
,
November 2025 in “Journal of the American Academy of Dermatology” In this randomized, placebo-controlled trial, adults with severe chronic alopecia areata who received deuruxolitinib showed significant hair regrowth compared to placebo over 24 weeks, and the treatment was generally well-tolerated, though long-term effects remain unexamined.
In this retrospective study, researchers found that baricitinib was effective for treating moderate to severe alopecia areata, with response rates in 24 patients comparable to existing real-world data, and no new safety concerns were identified.
7 citations
,
March 2023 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This letter discusses the potential of the Janus kinase 1 inhibitor abrocitinib for treating oral lichen planus but provides no new research findings.
January 2022 in “Lumbung Farmasi: Jurnal Ilmu Kefarmasian/Lumbung Farmasi” In this experimental study, researchers found that a hair tonic combining celery leaf extract and honey, specifically Formula B, showed the highest potential for promoting hair growth in rabbits, with outcomes comparable to a minoxidil control.
June 2026 in “International Journal of Innovative Science and Research Technology (IJISRT)” This review explores both traditional Ayurvedic uses and modern scientific findings on Japa Pushpa (Hibiscus rosa-sinensis), suggesting it may benefit cardiovascular health and metabolic balance as a herbal tea, but emphasizes the need for further clinical validation.
November 2025 in “Journal of the European Academy of Dermatology and Venereology” This study found that JAK inhibitor treatment in patients with alopecia areata was associated with a lower incidence of major depressive disorder and decreased antidepressant usage.
12 citations
,
January 2024 in “Journal of the American Academy of Dermatology”
March 2025 in “Journal of Neonatal Surgery” This review focuses on the significant pharmacological properties and therapeutic potential of phytosterols, terpenoids, flavonoids, and phenolic compounds from the endangered plant Nardostachys Jatamansi, highlighting their diverse applications in disease prevention and treatment.
August 2019 in “Pharmacoscript” This study found that a 3:2 combination of pandanus and sansevieria leaf extracts showed the best hair growth activity compared to using each extract alone.
2 citations
,
July 2023 in “Journal of cosmetic dermatology” In this study, JAK inhibitors like baricitinib and ruxolitinib were found to be more effective and caused fewer discontinuations due to adverse events in adults with alopecia areata compared to therapies like dupilumab and apremilast, highlighting the need for more high-quality comparative trials.
February 2024 in “Australasian journal of dermatology” This research letter discusses the use of Janus kinase inhibitors for treating lichen planopilaris, although specific results or conclusions from the study are not provided.
June 2020 in “Dermatologic therapy” Using Janus kinase inhibitors (JAKi) in COVID-19 treatment requires careful consideration due to their immunosuppressive effects.
September 2023 in “Jurnal MIPA (edisi elektronik)” This study formulated and evaluated the physical stability of hair tonic preparations using lime extract (Citrus aurantifolia) at varying concentrations. The researchers found that the tonics exhibited good physical stability, as indicated by meeting Indonesian National Standards, even after undergoing temperature cycling tests.
2 citations
,
June 2022 in “Molecules” This study demonstrated that an ethanol extract of Connarus semidecandrus Jack showed potential anti-androgenic alopecia effects in a testosterone-induced model, suggesting a possible treatment option for hair loss.
January 2024 in “Molecules (Basel. Online)” In this study, researchers examined juglone's potential as a restoring agent for hair keratin damaged by permanent or bleaching treatments, finding that juglone formed Michael adducts with cysteine residues, leading to a more regular hair surface as observed via IR spectroscopy and SEM analysis.
August 2020 in “Prosiding Farmasi” This review explores the potential of Arabian Bidara leaves as a hair growth enhancer based on its shared chemical compounds with other known hair-fertility-promoting plants, but it reports no new experimental results.
August 2019 in “Pharmacoscript” This study found that a combination of pandanus and sansevieria leaf extracts at a 3:2 ratio showed improved hair growth activity compared to individual extracts and controls.
2 citations
,
August 2018 in “Journal of pharmacopolium” This study found that a combination extract of pandanus and sansevieria leaves at a 3:2 ratio showed better hair growth activity than either extract alone.
October 2023 in “The Open Dermatology Journal” Baricitinib is effective for severe alopecia areata with manageable side effects, mainly upper respiratory infections.
April 2025 in “Drug Design Development and Therapy” This study observed that the herbal extract WJWE promoted hair growth and protected hair follicle cells in a DHT-induced murine model of androgenetic alopecia, potentially by engaging the SIRT1/JNK/p38 MAPK and Wnt5A/β-Catenin signaling pathways.