14 citations
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January 2020 in “Mediterranean Journal of Rheumatology” This review discusses the development of Janus kinase inhibitors for dermatologic diseases and reports no new results; the authors note the need for further research on their efficacy and safety.
June 2025 in “British Journal of Dermatology” This study reviewed therapies for alopecia areata and suggests that Janus kinase inhibitors, such as baricitinib and upadacitinib, show promise in treating both alopecia areata and associated immune-mediated inflammatory diseases.
6 citations
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May 2023 in “Drugs” This study reports that baricitinib was more effective than placebo in promoting hair growth in adults with severe alopecia areata after 36 weeks of treatment in clinical trials.
16 citations
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August 2023 in “JAAD Case Reports” This review discusses the unclear etiology and potential contributing factors of frontal fibrosing alopecia and reports no new clinical findings.
January 2026 in “Skin Health and Disease” This study conducted a survey among consultant dermatologists in Ireland to explore their use of JAK inhibitors for treating alopecia areata, acknowledging challenges posed by the lack of global guidelines and long-term safety data.
August 2025 in “Dermatology and Therapy” This review reports that three JAK inhibitors—baricitinib, ritlecitinib, and deuruxolitinib—have gained FDA approval for treating alopecia areata due to their demonstrated efficacy in fostering hair regrowth in clinical trials.
May 2023 in “Jurnal Penelitian Farmasi & Herbal” In this study, researchers developed cucumber-based hair tonics and tested their physical stability, finding them to be homogenous and meet requirements for color and pH, suggesting potential use as a remedy for hair loss.
1 citations
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January 2023 in “Portuguese Journal of Dermatology and Venereology” This review covers the use of JAK inhibitors in treating various dermatological conditions, emphasizing their potential while noting ongoing safety concerns with oral treatments; no new clinical results are provided.
September 2023 in “Journal of the American Academy of Dermatology” This study found that oral Janus kinase inhibitors were effective in treating alopecia areata, with a clinical response rate of 48.3%, though further research is needed to assess long-term effects.
January 2026 in “International Journal of Clinical Research” This collection of abstracts from the 2025 IJCR Global Summit documents a diverse array of clinical research topics, with no new study results as they remain in their original submission format without peer review.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The researchers developed a hair serum using rosemary essential oil and ficus bengalensis aerial roots, and successfully evaluated its viscosity, pH, and color.
10 citations
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January 2023 in “Acta dermato-venereologica” In this study, deuruxolitinib and baricitinib showed promising efficacy in treating alopecia areata, but effectiveness varied with dosage and further trials are needed to confirm these results.
August 2023 in “International journal of research in dermatology” This review suggests that oral Janus kinase inhibitors like tofacitinib, ruxolitinib, and baricitinib show promise for treating alopecia areata in adults, both in terms of efficacy and safety.
April 2024 in “Frontiers in pharmacology” This study compared JAK inhibitors for moderate-to-severe alopecia areata and found brepocitinib 30mg and deuruxolitinib 12mg to be most effective, though deuruxolitinib may cause more adverse events. Further research is needed for long-term efficacy and safety.
1 citations
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December 2022 in “The Nishinihon Journal of Dermatology” This source reports that based on international Phase 3 trial results, the JAK1/2 inhibitor baricitinib was approved in Japan in June 2022 for treating extensive alopecia areata, offering a potentially useful treatment option.
1 citations
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January 2019 in “Research Journal of Pharmacy and Technology” This review presents analytical methods for estimating Thuja occidentalis in homeopathic mother tincture but reports no new clinical results, emphasizing its broad application in homeopathy.
January 2024 in “Journal of Crohn's and colitis” This study reports that JAK inhibitors were effective in inducing remission in ulcerative colitis patients and presented an acceptable safety profile with a range of manageable side effects.
73 citations
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March 2010 in “Food and Chemical Toxicology” This study found that Zizyphus jujuba essential oil enhanced hair growth in mice, with the 1% and 10% concentrations showing increased hair length compared to control.
1 citations
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June 2023 in “American Journal of Clinical Dermatology” In two phase 3 clinical trials, this study found that adults with severe alopecia areata receiving baricitinib experienced significant hair regrowth on the scalp, eyebrows, and eyelashes over 36 weeks compared to placebo, although longer-term data are needed to fully assess benefits and risks.
2 citations
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March 2022 in “Modern Rheumatology Case Reports” In this study, a case of a patient with dermatomyositis and alopecia universalis showed successful treatment with tofacitinib, suggesting potential responsiveness to janus kinase inhibitors.
This study found that a 10% hibiscus leaf extract hair tonic demonstrated better hair growth activity than 2% minoxidil in rabbits but caused eye irritation.
6 citations
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February 2023 in “Journal of the American Academy of Dermatology” This article addresses the pathogenesis of alopecia areata and discusses the emerging role of oral and topical JAK inhibitors in its treatment, but reports no new clinical findings.
26 citations
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November 2002 in “Planta medica” In this study, the methanol extract of Cercidiphyllum japonicum heartwood was found to stimulate the proliferation of mouse hair epithelial cells, with several isolated compounds showing significant proliferative activities.
11 citations
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April 2015 in “EBioMedicine” This research highlights that JAK inhibitors, such as baricitinib, may effectively reverse symptoms of alopecia areata by targeting specific immune pathways, though safety and efficacy require further investigation.
January 2020 in “Elsevier eBooks” This review discusses the potential health benefits of Indian gooseberries, including blood glucose management and cardiovascular health, and highlights the need for additional research; no new clinical results are reported.
223 citations
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September 2018 in “Rheumatology” This review examines clinical data on the efficacy and safety of JAK inhibitors used for immune-mediated conditions beyond rheumatoid arthritis, highlighting their potential therapeutic roles in various inflammatory diseases.
3 citations
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May 2023 in “Clinical drug investigation” This study reviewed the safety of JAK inhibitors for alopecia areata, finding that common side effects included headache and acne, with varying risks for respiratory infections and no increased risk of serious adverse events.
2 citations
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September 2024 in “Journal of the American Academy of Dermatology” Deuruxolitinib significantly helps regrow scalp hair in adults with moderate to severe alopecia areata.
March 2024 in “Journal of Society of Cosmetic Chemists of Japan” In this study, a medicated hair growth tonic containing RJ extract increased hair counts, the proportion of anagen phase hairs, and scalp moisture in human trials, although the specific role of RJ in hair growth remains unclear due to other active ingredients.
December 2017 in “JURNAL FARMANESIA” In this study, the researchers found that using dragon fruit peel extract in a gray hair dye formulation, along with specific adjuvants, produced a dark black color on gray hair, demonstrating its potential as a natural colorant alternative to synthetic dyes.