research Drug News and Therapeutic News
JAK inhibitors help treat some diseases but may increase risks of blood clots and cancer in certain patients.
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research The Use of Tofacitinib in the Treatment of Immune-Mediated Universal Alopecia in a Patient with Systemic Lupus Erythematosus: A Case Report
Tofacitinib improved arthritis and partially improved hair loss in a lupus patient without side effects.
research Characterization of Novel TMEM173 Mutation Causing a Lupus- and SAVI-Like Phenotype, Modified by Polymorphisms in TMEM173 and IFIH1
A new mutation in the STING protein causes a disease with lupus-like symptoms and responds well to a specific inhibitor treatment.
research Tissue Engineered Human Hair Follicles from Genetically, Environmentally, and Extrinsically Reprogrammed Dermal Papilla Cells
Researchers developed a method to grow human hair follicles using 3D-printed skin models and modified cells.
research Human Hair Follicle Transcriptome Profiling: A Minimally Invasive Tool to Assess Molecular Adaptations Upon Low-Volume, High-Intensity Interval Training
Hair follicle analysis can track body changes from high-intensity interval training.
research Tofacitinib as a Pragmatic Treatment Choice for Alopecia Areata: A Retrospective Review
Tofacitinib was found to be a safe and effective treatment for hair regrowth in patients with alopecia areata.
research Review of Treatment for Alopecia Totalis and Alopecia Universalis
No treatment is completely effective for alopecia totalis and alopecia universalis.
research Gene Expression Signatures and ALADIN Score Correlate with Response of Alopecia Areata Patients to Treatment with JAK Inhibitors
The ALADIN score can predict how well patients with alopecia areata will respond to JAK inhibitor treatments.
research Treatment of Lichen Planopilaris With Janus Kinase Inhibitors
Janus kinase inhibitors may help treat lichen planopilaris.
research Alopecia Areata Treatment: Past, Present, And Future
New treatments for Alopecia Areata, like JAK inhibitors, are effective, and future research is exploring advanced therapies.
research Unraveling Vitiligo: From Immune Mechanisms to Promising Therapeutic Strategies
Vitiligo treatments include JAK inhibitors, UVB phototherapy, and dietary changes, with emotional support being important.
research Experience in Treating Multifocal Alopecia Areata in a Child with JAK Kinase Inhibitors
JAK inhibitors like tofacitinib may effectively treat alopecia in children without major side effects.
research Patient Experience of Off-Label Janus Kinase Inhibitor Use for Alopecia Areata in a Cohort of 34 Patients From a Single UK Practitioner: Exploring Changing Trends in Healthcare Provision and Access to Drug Treatments
Patients with alopecia areata face challenges accessing Janus kinase inhibitors, but some see positive results.
research Hair Today, Gone Tomorrow: Potential of Tofacitinib and Ruxolitinib in Treating Hair Loss
Two drugs, tofacitinib and ruxolitinib, may help regrow hair by activating hair follicles.
research Topical Ruxolitinib for the Treatment of Alopecia Universalis
Topical Ruxolitinib may safely treat severe hair loss.
research LB789 Novel IFNγ Aptamer TAGX-0003 Protected Hair Follicles from Immune Privilege Collapse and Reversed Alopecia Areata-Like Phenotype in Humanized Mouse Model
TAGX-0003 protected hair follicles and reversed alopecia areata in a mouse model.
research Characterization of a Murine Model of AA Induced by Adoptive Transfer of Cultured Lymph Node Cells
The study developed a mouse model for Alopecia Areata that responds to treatment, useful for future research.
research A Review of JAK Inhibitors for Treatment of Alopecia Areata in the Military Health Care System
JAK inhibitors like baricitinib and ritlecitinib are effective new treatments for severe alopecia areata.
research Targeting Pathogenic MICA-NKG2D Interactions by Statins: A Novel Adjunct Treatment Strategy for Alopecia Areata Management?
Statins may help treat alopecia areata by reducing harmful immune interactions.
research The Role of Janus Kinase Inhibitors in the Treatment of Alopecia Areata: A Systematic Review
Janus kinase inhibitors show promise for treating alopecia areata but need more research for confirmation.
research JAK-Inhibitors in Dermatology: Current Evidence and Future Applications
JAK-inhibitors are effective for treating psoriasis and show promise for other skin diseases.
research High Throughput T Cell Receptor Sequencing Identifies Clonally Expanded CD8+ T Cell Populations in Alopecia Areata
Expanded CD8+ T cells are linked to Alopecia Areata and may cause relapse after treatment.
research A Systematic Review on the Treatment of Androgenetic Alopecia
Doctors should prescribe Minoxidil, Finasteride, and Dutasteride for treating androgenetic alopecia.
research The Changing Landscape of Managing Hair Loss: A 30-Year Perspective
There have been major advances in diagnosing and treating hair loss over the last 30 years, with new drugs and improved hair transplant techniques.
research Effectiveness of Tofacitinib in Pre-Adolescent Alopecia Areata: A Retrospective Case Series and Literature Review
Tofacitinib is a safe and effective treatment for hair loss in children with Alopecia Areata.
research Review of the Literature: Topical JAK Inhibitors Showing Promise for Hair Loss
Topical JAK inhibitors may help treat hair loss.
research Androgenetic Alopecia Pattern Hair Regrowth in Patients with Alopecia Areata Treated with Oral JAK Inhibitors
Oral JAK inhibitors help regrow hair in alopecia patients.
research Real-World Experience of Efficacy and Safety of Baricitinib in Korean Patients with Severe Alopecia Areata
Baricitinib 4 mg is effective and safe for treating severe alopecia areata.
research In-Silico Study of Bioactive Compounds of Natural Materials as a JAK-Signal Transducer and Activator of Transcription Inhibitor for Anti-Alopecia
Three compounds from Dadap leaves may help treat hair loss.
research Safety and Efficacy of the JAK Inhibitor Tofacitinib Citrate in Patients with Alopecia Areata
Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.