A Systematic Review on the Treatment of Androgenetic Alopecia

September 2022 in “ IP Indian journal of clinical and experimental dermatology ”

Dilip N R Kumar, Laxmi Horatti, Abhram Rayapati

androgenetic alopecia JAK inhibitors Minoxidil Finasteride Dutasteride Rogaine Propecia

TLDR Doctors should prescribe Minoxidil, Finasteride, and Dutasteride for treating androgenetic alopecia.

The systematic review on the treatment of androgenetic alopecia by Horatti, Kumar, and Rayapati highlights the significant impact of this genetic disorder, particularly on women's emotional well-being. The review discusses the epidemiology, early signs, symptoms, and causes of androgenetic alopecia. Despite limited advancements in treatment over the past 30 years, recent investigations into JAK inhibitors offer hope for a permanent cure. The authors recommend that physicians prescribe pharmacological drugs such as Minoxidil, Finasteride, and Dutasteride as the first line of therapy for treating androgenetic alopecia.

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Research cited in this study

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research Guidelines for the Diagnosis and Treatment of Male-Pattern and Female-Pattern Hair Loss, 2017 Version

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A Randomized, Active- and Placebo-Controlled Study of the Efficacy and Safety of Different Doses of Dutasteride Versus Placebo and Finasteride in the Treatment of Male Subjects with Androgenetic Alopecia

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Dutasteride 0.5 mg works better than finasteride and placebo for increasing hair in men with hair loss.

A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

research A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

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5% minoxidil works better for hair growth and density, with minor irritation.

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Treatments for common hair loss include minoxidil, finasteride, and hair transplantation.

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community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 3 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community Rare Non responder to Finasteride, Dutasteride, and oral minoxidil

in Minoxidil 78 upvotes 2 years ago

A user did not respond to finasteride, dutasteride, and oral minoxidil for hair loss after four years of treatment and is considering scalp micropigmentation (SMP). Other users suggest the hair loss pattern may indicate alopecia areata and recommend seeing a dermatologist.

community any news about DUPA (Diffuse unpatterned alopecia)?

in Research/Science 10 upvotes 3 years ago

The conversation discusses diffuse unpatterned alopecia (DUPA) and its possible causes, including sensitivity to DHT, not being androgenic alopecia, being diffuse alopecia areata, or hormonal issues. Treatments mentioned include topical melatonin, Clobetasol Propionate for alopecia areata, and the lack of results from using finasteride, dutasteride, and minoxidil.

community DUPA - 20 YO - Non responder to everything

in Finasteride/Dutasteride 13 upvotes 1 year ago

A 20-year-old user experienced worsening hair loss despite using various treatments including topical and oral minoxidil, finasteride, and dutasteride. Other users suggested additional treatments like JAK inhibitors, RU58841, and lifestyle changes, but the user remains skeptical and frustrated.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Dutasteride has been nuking me

in Finasteride/Dutasteride 156 upvotes 4 months ago

The user experienced significant hair loss after 9 months of using 0.5mg dutasteride and oral minoxidil, possibly due to alopecia areata. It is advised to consult a doctor for accurate diagnosis and treatment, as dutasteride and finasteride may not be effective.

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