Experience in Treating Multifocal Alopecia Areata in a Child with JAK Kinase Inhibitors

    July 2024 in “ Medical alphabet ”
    A.M. Dogov Dogov
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    TLDR JAK inhibitors like tofacitinib may effectively treat alopecia in children without major side effects.
    The study presents a clinical case of treating multifocal alopecia areata in a 9-year-old child using oral tofacitinib, a JAK inhibitor. Over a 6-month treatment period, the patient experienced full recovery of hair growth on the scalp, with no significant clinical or biochemical abnormalities observed during treatment or for a year after discontinuation. Additionally, there was no recurrence of hair loss 12 months post-treatment. The findings suggest that JAK inhibitors could be effective for treating alopecia in children, though further data from randomized controlled trials are needed to ensure their safe use.
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