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research Efficient Generation of Skin Organoids from Pluripotent Cells via Defined Extracellular Matrix Cues and Morphogen Gradients in a Spindle‐Shaped Microfluidic Device
This study found that generating pluripotent stem cell-derived skin organoids in a 3D bioprinted hydrogel device improved keratinocyte differentiation and hair follicle formation while reducing necrosis.
research Biologically Driven Innovations in Aesthetic Surgery: Advances in Regenerative and Cellular Therapies
This review found that adipose-derived stem cells and stromal vascular fraction have robust clinical benefits in aesthetic surgery, particularly in facial rejuvenation, scar treatment, and volumetric restoration, with favorable safety profiles.
research Functional endoscopy techniques for tracking stem cell fate
This review discusses recent advances in imaging techniques for monitoring stem cells in vivo and reports no new results; it suggests directions for future development in endoscopic molecular imaging tools.
research 596 Application of an artificial intelligence (AI) photographic device to track platelet-rich plasma treatment outcomes in females with alopecia
This study explored the use of an AI-driven device, HairMetrix, to quantitatively assess the effects of PRP treatments on scalp health in two Caucasian women with androgenetic alopecia, reporting increases in average hair width and follicle count after one treatment.
research Chondrogenic differentiation of human scalp adipose‐derived stem cells in Polycaprolactone scaffold and using Freeze Thaw Freeze method
In this study, adipose-derived stem cells from human scalp were successfully directed towards chondrocyte differentiation, with TGF-beta3 and BMP-6 growth factors proving effective for in vitro chondrogenesis.
research AMERICAN SOCIETY FOR DERMATOLOGIC SURGERY, INC.
New techniques and findings in dermatologic surgery show improved pain management, safer liposuction, better hair transplantation, and effective treatments for skin conditions.
research Journal Impact Factor for the Indian Journal of Plastic Surgery
This source reports that the Indian Journal of Plastic Surgery received its first Journal Impact Factor of 0.8 for 2022, a notable achievement highlighting its significant contributions to the field of plastic surgery.
research Disposable Linear Slot Punches
This announcement from Redfield Corporation introduces the first disposable linear slot punches for hair restoration surgery, with sharpness guaranteed for up to 500 recipient sites.
research Trajectory of hiPSCs derived neural progenitor cells differentiation into dermal papilla-like cells and their characteristics
In this study, researchers differentiated human induced pluripotent stem cells into dermal papilla-like cells and observed gene expression dynamics during five stages of dermal differentiation, demonstrating the potential of these cells to interact with epidermal cells in functional assays.
research A Novel Approach to Pattern Dermal Papilla Spheroids in Dermal–Epidermal Composites Using Non-Adherent Microwell Arrays
In this study, researchers used a 3D printing technique to spatially pattern human dermal papilla cell spheroids in a collagen matrix, enhancing skin and hair regeneration in a mouse model, with notable upregulation of key genes for hair follicle formation compared to traditional cell cultures.
research Generation of iPS-derived model cells for the analysis of hair development
In this study, researchers developed a model using iPS-derived cells to trace and evaluate hair follicle differentiation, which could aid in the development of hair growth treatments.
research Isolating subpopulations of human epidermal basal cells based on polyclonal serum against trypsin-resistant CSPG4 epitopes
This study reveals that CSPG4-positive basal cell keratinocytes show distinct global gene expression from CSPG4-negative cells, despite similar colony-forming efficiency.
research Probing neuronal functions with precise and targeted laser ablation in the living cortex
This study demonstrated that ablation of individual somatostatin-expressing interneurons increased activity in nearby neurons of the mouse motor cortex during motor learning.
research Discovery of Orally Available Prodrugs of Itaconate and Derivatives
This study identified orally available itaconate derivatives that improve cellular permeability and bioavailability, with specific POC-based prodrugs showing significant inhibition of inflammatory cytokines in human epidermal keratinocytes and favorable oral pharmacokinetics, highlighting their potential for treating systemic and skin disorders.
research Real-world single-center experience with 10 cases of generalized pustular psoriasis successfully treated with ixekizumab
Ixekizumab effectively treats generalized pustular psoriasis.
research Orders & Contracts
This study found that using particle-based antigen delivery in combination with cyanoacrylate skin surface stripping is an effective needle-free method for targeting HIV-1 p24 protein to skin cells, enhancing transcutaneous vaccination potential.
research Injectable Thermosensitive Placental ECM –Copper Hydrogel With Endothelial Progenitor Cells for Pressure Ulcer Repair
This study found that a hydrogel made from human placenta-derived ECM, copper, and endothelial progenitor cells significantly enhanced pressure ulcer healing in a mouse model by improving wound closure and tissue regeneration.
research Advanced 3D/4D Bioprinting of Flexible Conductive Materials for Regenerative Medicine: From Bioinspired Design to Intelligent Regeneration
This review introduces a framework to integrate bioinspired conductive materials and advanced 3D/4D printing in regenerative medicine for dynamic, responsive tissue regeneration, emphasizing the potential of smart scaffolds to adapt to physiological cues.
research Photoablation at single cell resolution and its application in the Drosophila epidermis and peripheral nervous system
This study describes a new method using near infrared femtosecond laser pulses to precisely ablate individual cells in the Drosophila epidermis and peripheral nervous system without damaging surrounding tissues, allowing for detailed observation of cellular responses post-ablation.
research Platelet-rich plasma therapy: key infection prevention practices and strategies for safety risk reduction
This article discusses developing a standardized operating procedure for PRP administration to align with infection prevention regulatory standards and reports no new clinical results.
research Pain relief and dermatological changes in complex regional pain syndrome with peripheral nerve stimulation
This case report described how peripheral nerve stimulation provided significant pain relief and reversal of dermatological symptoms for a female patient with complex regional pain syndrome after conventional treatments failed.
research SYNTHETIC PIEZOELECTRIC POLYMERS AND THEIR APPLICATIONS IN MEDICINE; 2020-2021 OVERVIEW
This review discusses synthetic piezoelectric polymers within the smart polymer family, detailing their applications in various medical fields, but reports no new experimental results.
research Polynucleotides High Purification Technology: A Real-World Prospective Study in a Hospital Outpatient Setting Supports PN HPT as a Regenerative Medicine Option for Acne Scar Management
In this study, combining Polynucleotides High Purification Technology with hyaluronic acid significantly reduced atrophic post-acne scar areas and improved Goodman-Baron scores in a majority of treated patients over six months, reaffirming the approach's beneficial effects in a real-world outpatient setting.
research Clinical Efficacy and Safety of Pulsed Dye Laser Combined with Pingyangmycin on Hyperplastic Scar after Acne
This study found that combining pulsed dye laser with pingyangmycin improved treatment efficacy, scar repair, skin condition, and patient satisfaction in treating post-acne hyperplastic scars, compared to laser alone, without increasing adverse reactions.
research Peer Review #2 of "Establishment of an immortalized mouse dermal papilla cell strain with optimized culture strategy (v0.2)"
This study developed and validated an optimized culture method for dermal papilla cells, leading to the establishment of an immortalized cell strain called iDP6, which resembles primary DP cells in key characteristics.
research Interstitial pneumonia with autoimmune features: challenges and controversies
This review covers the current status of the interstitial pneumonia with autoimmune features (IPAF) category, pointing out the need for revision of its criteria to establish it as a standalone diagnostic term, but reports no new clinical findings.
research The Anti-Muscle Atrophy Effects of Ishige sinicola in LPS-Induced C2C12 Myotubes through Its Antioxidant and Anti-Inflammatory Actions
This study found that Ishige sinicola ethanol extract and its butanol fraction can protect against lipopolysaccharide-induced muscle atrophy in C2C12 myotubes through antioxidant and anti-inflammatory activities.
research STITCH: Augmented Dexterity for Suture Throws Including Thread Coordination and Handoffs
In this study, the researchers developed an advanced robotic system called STITCH for performing suture tasks, which completed an average of 2.93 sutures autonomously and 4.47 sutures with human intervention in physical trials.
research Current stem cells technologies used in medicine
This review summarizes advancements in stem cell technologies, highlighting their effectiveness in disease treatment and tissue reconstruction for conditions such as nerve palsy and myocardial infarction, supported by pre-clinical and clinical studies.