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Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.

The document reports a rare case of ECCL with a new association with optic disc colobomas.

Vismodegib is effective for basal cell carcinoma but has severe side effects.

A 24-month-old Nigerian girl developed early puberty with no family history, needing treatment her family couldn't afford.

Most people on isotretinoin had chapped lips, but only a few stopped the medicine due to side effects.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Taking too many vitamin and mineral supplements can cause serious health problems.

Get head MRI for babies with achondroplasia early, use free immunoglobulin light chains to detect certain neurodevelopmental disorders, and video calls work for speech therapy in patients with facial anomalies.

Isotretinoin is a preferred treatment for severe acne, often leading to long-term improvement, but requires careful monitoring due to potential side effects.

A new MTX2 gene mutation caused a severe genetic disorder in a young Chinese girl.

MRI helps distinguish between pituitary adenomas and craniopharyngiomas, guides treatment for pediatric CNS tumors, and assesses rhinocerebral mucormycosis with a high mortality rate in transplanted patients.

Acitretin is effective for severe skin conditions but has significant side effects and requires careful monitoring.

Pica disorder in central Iraq is mainly found in females and is linked to low iron levels; treatment with iron improves most patients.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

High levels of cortisol in hair are linked to a greater risk of brain aneurysm rupture.

Spironolactone may cause increased brain pressure in some patients.

Long-term low-dose Vitamin A intake may cause increased brain pressure.

Cyclosporine-A can cause serious blood clots in the brain, so patients need careful monitoring.

Square-shaped hair loss can occur after treating a brain aneurysm due to localized radiation exposure.

A small forehead lesion led to the discovery of a significant brain arteriovenous malformation in a young girl.

A girl with symptoms like an autoimmune disorder actually had HIV and a fungal infection, which was hard to diagnose and treat, leading to her death.

Hair restoration surgery in patients with prior neurosurgery or radiation treatment can have risks like infection and poor wound healing, so it's important to discuss these with the patient.

A woman's new seizures were caused by a brain tumor likely linked to her past cancer treatment, and choosing safe seizure medications is important for women who can have children.

Adrenal disorders can cause lasting brain and behavior issues in children.

A rare skin cancer caused hair loss and spread, needing multiple treatments.

A man experienced life-threatening shock after swallowing hair growth solution.

The document concludes that specific hair and blood vessel abnormalities in infants with seizures and developmental issues may indicate Menkes disease, which lacks a cure and is often fatal by age 3.

Some vitamins, amino acids, and alternative medicines can cause serious side effects, including bone, muscle, and skin issues, and healthcare professionals should be aware of these risks.

Lupus can be a rare cause of high calcium levels in the blood.

The authors agree they didn't follow the original criteria strictly but found the Ottawa rule effective in all tested patients and suggest it might have wider use.