In this study on patchy alopecia areata treatment involving 20 patients, TCA (triamcinolone acetonide) injections showed a significantly better response and minimal side effects compared to superficial cryotherapy.
2 citations
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March 1964 in “Archives of Dermatology” This study found no significant difference in the therapeutic response to intralesional triamcinolone acetonide at concentrations of 2.5, 5, and 10 mg/mL for various dermatologic conditions.
35 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This study found that intralesional triamcinolone acetonide is effective for treating localized patchy alopecia areata, with dermoscopy aiding in early detection of clinical response and adverse effects.
This study found that combining intralesional PTX and corticosteroids may enhance treatment outcomes for alopecia areata, with PTX showing better long-term effects compared to corticosteroids alone.
4 citations
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January 2022 in “Drug design, development and therapy” This study demonstrated that intramuscular corticosteroids were effective for severe alopecia areata, with significant hair regrowth in 80.2% of patients, though a high relapse rate was noted post-treatment. Nail involvement and disease duration over six months negatively impacted outcomes.
September 2024 in “Egyptian Journal of Dermatology and Venerology” This study found that intralesional injection of triamcinolone acetonide combined with latanoprost (a PGF2α analog) was more effective in treating localized alopecia areata, showing higher treatment response rates and greater reduction in severity scores compared to other treatments.
11 citations
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March 2018 in “Anais Brasileiros de Dermatologia” This article describes the DOAJ as a comprehensive index of diverse open access journals, emphasizing its commitment to freely providing quality content online, and reports no new findings.
July 2024 in “JAAD Case Reports” This study reports two cases of central serous chorioretinopathy developing after intralesional corticosteroid injections to the scalp for alopecia areata, suggesting a potential association that warrants cautious use and monitoring for ocular complications.
60 citations
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October 2009 in “PubMed” This study reports that intralesional triamcinolone acetonide was effective and well-tolerated for treating extensive alopecia areata in patients who often showed specific initial hair characteristics.
1 citations
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January 2022 in “The Egyptian Journal of Hospital Medicine ” This study found that both superficial cryotherapy and intralesional corticosteroid injections significantly improved hair growth in patients with alopecia areata, with similar efficacy between the two treatments, establishing cryotherapy as a simple and noninvasive treatment option.
16 citations
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July 2000 in “Dermatologic surgery” This paper contains author contact information and disclosures without reporting new research findings or results.
4 citations
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October 2023 in “Journal of Medicine and Life” In this study, UDCA treatment reduced inflammation, oxidative stress, and cartilage damage in rats with experimentally induced rheumatoid arthritis, suggesting potential anti-rheumatoid arthritis properties.
7 citations
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June 2017 in “The Journal of Dermatology” This abstract notes a disclaimer about supporting information and does not report new research findings.
August 2026 in “South Asian Journal of Health Sciences” In this case report, a 35-year-old man developed avascular necrosis after receiving intradermal corticosteroid injections for alopecia areata, marking the first documented instance of this side effect from such treatment.
1 citations
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May 2026 in “Journal of Dermatological Treatment” This case report suggests that starting selective Janus kinase 1 inhibition may improve alopecia in a patient with rheumatoid arthritis who was not responding to TNF-α inhibitor therapy and corticosteroids.
51 citations
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July 2003 in “Annals of the Rheumatic Diseases” This case study reports a successful use of co-trimoxazole in treating a 13-year-old girl with symptoms suggestive of autoimmune disorders and relapsing polychondritis.
This study, involving patients with early rheumatoid arthritis, found that treatment regimens combining methotrexate and glucocorticoids, with or without initial high-dose methylprednisolone, showed higher remission rates over one year compared to methotrexate or leflunomide alone, and all regimens were generally well-tolerated.
22 citations
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May 2017 in “Journal of dermatological treatment” This study found that BD 1/4 dilution was the most effective corticosteroid concentration for intralesional injection to treat localized alopecia areata in adults, with fewer adverse effects than TA.
August 2025 in “International Journal of Scientific Research” This study found that both intralesional PRP and corticosteroids are effective for alopecia areata, but PRP offers higher patient satisfaction and fewer side effects, despite a slower initial response.
34 citations
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November 1974 in “Archives of Dermatology” This report discusses historical cases of visual side effects from scalp corticosteroid injections for alopecia areata and attributes their rarity now to improved injection techniques and smaller particulate sizes in suspensions.
6 citations
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December 2015 in “Journal of Dermatological Case Reports” This case report highlights that intradermal testing may be more effective than patch testing for diagnosing delayed hypersensitivity reactions to intralesional corticosteroids like triamcinolone acetonide.
August 2023 in “The Journal of Dermatology” This retrospective study found that intralesional betamethasone injections led to significant repigmentation in scalp vitiligo patients without leukotrichia, suggesting it as an effective treatment option.
August 2025 in “Zanco Journal of Medical Sciences” In this interventional therapeutic study, both intralesional triamcinolone acetonide and vitamin D3 showed significant improvement in alopecia areata, with terminal regrowth more frequently observed in the steroid group, although differences were not statistically significant.
15 citations
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June 1961 in “Archives of Dermatology” This report details observations from four patients with alopecia areata who received intralesional triamcinolone injections to assess its effectiveness for promoting hair regrowth in localized areas.
This study found that both intradermal BCG vaccine and intralesional triamcinolone acetonide were similarly effective for treating patchy alopecia areata, though intralesional triamcinolone was preferable due to fewer side effects associated with BCG vaccine.
18 citations
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January 2015 in “International Journal of Trichology” This study found that intralesional steroid treatment led to significantly more hair regrowth in alopecia areata patients than narrow band ultraviolet B therapy, while their combination did not enhance effectiveness.
4 citations
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December 2024 in “Archives of Dermatological Research” September 2025 in “Acta Dermato Venereologica” Intralesional corticosteroids may be more effective than cryotherapy for hair regrowth in alopecia areata.
1 citations
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August 2024 in “Journal of Cosmetic and Laser Therapy” This study found that intralesional vitamin D3 achieved similar effectiveness to triamcinolone acetonide for treating patchy alopecia areata but was associated with fewer adverse effects and higher patient satisfaction.
June 2020 in “Annals of the Rheumatic Diseases” This study surveyed patients with idiopathic inflammatory myopathy and found that glucocorticoid treatment commonly leads to adverse effects, particularly sleep disturbance, mood swings, and weight gain, with more severe effects reported by female patients.