research Dermatology of Androgen-Related Disorders
Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.
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research Control of Human Hair Growth by Neurotrophins: Brain-Derived Neurotrophic Factor Inhibits Hair Shaft Elongation, Induces Catagen, and Stimulates Follicular Transforming Growth Factor Beta 2 Expression
Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.
research Polycystic Ovary Syndrome and the Risk of Obstructive Sleep Apnea: A Meta-Analysis and Review of the Literature
Adults with polycystic ovary syndrome are much more likely to have obstructive sleep apnea.
research Sulfation of Minoxidil by Multiple Human Cytosolic Sulfotransferases
Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.
research Multi-Therapies in Androgenetic Alopecia: Review and Clinical Experiences
Multiple treatments work best for hair loss.
research Maternal Western Diet Causes Inflammatory Milk and TLR2/4-Dependent Neonatal Toxicity
A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.
research The Investigation of Insulin Resistance and Metabolic Syndrome in Male Patients with Early-Onset Androgenetic Alopecia
Early balding men may have insulin resistance, but lifestyle changes can help.
research 17-Hydroxyprogesterone Responses to Gonadotropin-Releasing Hormone Reveal Distinct Phenotypes of Functional Ovarian Hyperandrogenism and Polycystic Ovary Syndrome
The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.
research Cushing Syndrome from Percutaneous Absorption of 1% Hydrocortisone Ointment in Netherton Syndrome
Low-potency steroids can cause serious side effects in people with skin conditions like Netherton syndrome.
research Skin Aging as a Mechanical Phenomenon: The Main Weak Links
Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.
research NUDT15, FTO, and RUNX1 Genetic Variants and Thiopurine Intolerance Among Japanese Patients With Inflammatory Bowel Diseases
Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.
research SLE and Serum Complement: Causative, Concomitant or Coincidental?
Low serum complement levels in SLE patients don't always match with disease flares; monitoring C3 and C4 is useful, but cell-bound complement products might better indicate disease activity.
research CD4+CD25+FoxP3+ Regulatory Tregs Inhibit Fibrocyte Recruitment and Fibrosis via Suppression of FGF-9 Production in the TGF-β1 Exposed Murine Lung
Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.
research The Effect of Weight Loss and Treatment with Metformin on Serum Vaspin Levels in Women with Polycystic Ovary Syndrome
Weight loss and metformin don't significantly change vaspin levels in women with PCOS.
research Systematic Review and Meta-Analysis of the Efficacy and Safety of Leflunomide and Methotrexate in the Treatment of Rheumatoid Arthritis
Leflunomide and methotrexate are equally effective for rheumatoid arthritis but have different side effects.
research Gender-Specific Association of Androgenetic Alopecia with Metabolic Syndrome in a Middle-Aged Korean Population
Female hair loss linked to metabolic syndrome, not in males.
research Gonadotropin-Releasing Hormone Agonist Treatment in Postmenopausal Women with Hyperandrogenism of Ovarian Origin
Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.
research Effect of Minoxidil on Blood Pressure and Hemodynamics in Severe Hypertension
research The Influence of Interferon on Healthy and Diseased Skin
Type I interferons play a key role in the development of various skin diseases.
research Oral Zinc Sulphate Causes Murine Hair Hypopigmentation And Is A Potent Inhibitor Of Eumelanogenesis In Vivo
Oral zinc sulphate reduces dark hair color in mice.
research The Clinical Management of Hirsutism
The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.
research Diagnostic Approach to Low-Renin Hypertension
Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.
research Thrombin Activatable Fibrinolysis Inhibitor and Other Hemostatic Parameters in Patients with Polycystic Ovary Syndrome
Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.
research Dermatologic Manifestations of COVID-19: A Comprehensive Systematic Review
COVID-19 can cause skin issues like chilblains and rashes, which may help in early detection, especially in patients without other symptoms.
research Annurca Apple Nutraceutical Formulation Enhances Keratin Expression in a Human Model of Skin and Promotes Hair Growth in a Randomized Clinical Trial
Annurca apple supplement safely increases hair growth and keratin in humans.
research The Diagnosis of Nonclassic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency Based on Serum Basal or Post-ACTH Stimulation 17-Hydroxyprogesterone Can Lead to False-Positive Diagnosis
Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.
research Hair Repigmentation Associated with the Use of Lenalidomide: Graying May Not Be an Irreversible Process
An 81-year-old man's white hair began to regain its original color while he was treated with lenalidomide, suggesting that graying hair might be reversible.
research A Multicenter Placebo-Controlled Clinical Trial on the Efficacy of Oral Ciclosporin A in the Treatment of Canine Idiopathic Sebaceous Adenitis Compared with Conventional Topical Treatment
Oral ciclosporin A and topical treatments both reduce hair loss and scaling in dogs with sebaceous adenitis, but using both together is most effective.
research An X-Linked Gene Involved in Androgenetic Alopecia: A Lesson to Be Learned from Adrenoleukodystrophy
Gene linked to common hair loss found, may lead to new treatments.
research Electron Paramagnetic Resonance Spectroscopy for Investigating Murine Telogen Skin After Spontaneous or Depilation-Induced Hair Growth
EPR spectroscopy showed that spontaneous hair growth results in thicker skin and less pigmented hair than depilation-induced growth.