30 citations
,
March 2017 in “ACS biomaterials science & engineering” This review discusses the structure and regenerative potential of hair follicles, highlighting their role in wound healing, stem cell populations, and keratin-based biomaterials, but it reports no new clinical results.
27 citations
,
January 2020 in “Experimental Dermatology” This review discusses the role of immune cells in mammalian hair cycle control and highlights their potential relevance to human hair cycling disorders, reporting no new clinical findings.
23 citations
,
February 1979 in “Veterinary Clinics of North America: Small Animal Practice” This review discusses the physicochemical properties, binding mechanisms, and factors affecting corticosteroid-binding globulin (CBG) functions, but reports no new clinical results.
22 citations
,
November 2024 in “Planta” This review highlights the potential of aromatic plants as natural antioxidants in cosmeceuticals, which may combat skin aging and promote rejuvenation by counteracting oxidative stress, offering a natural alternative to synthetic products with benefits like photoprotection and anti-wrinkle effects.
22 citations
,
May 2021 in “Nature Communications” This study found that in wound-induced hair neogenesis, African spiny mice and laboratory mice exhibit different morphogenetic field formation patterns related to tissue stiffness, suggesting evolutionary developmental biology advantages.
21 citations
,
September 2024 in “Cureus” This review explores the mechanisms, techniques, and clinical applications of microneedling, highlighting its advantages and challenges in skin rejuvenation, and discusses future innovations in the field as it continues to evolve.
21 citations
,
June 2018 in “Current Opinion in Genetics & Development” This review discusses recent advancements in regenerative medicine, including functional organ regeneration and the creation of mini-organs, and reports no new clinical results.
20 citations
,
October 2013 in “British Journal of Dermatology” The document concludes that clinicians should be aware of common hair and scalp disorders in women of African descent and that more research is needed to develop effective treatments.
19 citations
,
March 2018 in “Journal of Investigative Dermatology” This study indicates that transient Msx2 expression is critical for wound-induced hair follicle neogenesis, with distinct phases in the healing process essential for epidermal competence and hair regeneration.
18 citations
,
May 2016 in “Annals of Medicine” This paper reviews seven major systemic causes of hair loss and provides a clinical evaluation framework but reports no new experimental results.
16 citations
,
January 2020 in “Diabetes” In this study using diabetic rat models, the combination of AMD3100 and low-dose FK506 reduced wound healing time and improved microcirculation in diabetic foot ulcers, indicating a promising new systemic therapy.
16 citations
,
April 2012 in “Journal of mammalogy” Among Australian fur seals at one colony, this study found that alopecia, primarily affecting juvenile females, is linked to hair shaft fractures associated with low tyrosine and zinc levels, as well as higher pollutant exposure.
16 citations
,
December 2006 in “Expert Review of Dermatology” This review discusses the multifaceted roles of hair follicles in skin health, including potential contributions to skin neoplasias, and reports no new results.
15 citations
,
January 2015 in “Skin Pharmacology and Physiology” This study indicates that targeting the PTH/PTHrP receptor may potentially stimulate hair growth, particularly for chemotherapy-induced alopecia, as observed in hairless and cyclophosphamide-treated mice.
14 citations
,
April 2014 in “Medical Clinics of North America” This review discusses common skin conditions in primary care settings and provides guidance on differential diagnoses and selecting appropriate topical treatments, but it reports no new clinical results.
14 citations
,
July 2011 in “Clinics in plastic surgery” This review discusses the use of dermabrasion as an effective skin resurfacing technique for treating aging effects and reports no new clinical results.
12 citations
,
August 2016 in “Current opinion in genetics & development” In this study, researchers using the hair paradigm highlighted how periodic patterning and compartmentalization enable diverse regenerative behaviors, including region-specific renewal cycles and emergent properties like regenerative waves in organ populations.
8 citations
,
June 2008 in “Aktuelle Dermatologie” Early diagnosis and personalized treatment are crucial for managing different types of alopecia effectively.
8 citations
,
May 2024 in “PLoS Biology” This study on feather pattern formation in chicken skin found that inhibiting gap junctional intercellular communication can lead to the emergence of new feather buds in specific spatial patterns, suggesting that GJIC may facilitate Turing-type periodic patterning by propagating inhibitory signals over long distances.
7 citations
,
May 2020 in “Trends in molecular medicine” This study explored the immune environment of the hair follicle's bulge region and suggested that its unique signaling may prevent melanoma formation by lacking necessary proinflammatory signals for full oncogenic transformation, indicating potential strategies for melanoma prevention by replicating this immune-privileged environment.
7 citations
,
January 2013 in “BioMed research international” This review highlights surprising similarities between hair follicles and antler units, suggesting that a comparative study of their biology could benefit understanding in both areas without presenting new empirical findings.
6 citations
,
July 2015 in “Journal of Investigative Dermatology” Chicken feather gene mutation helps understand human hair disorders.
5 citations
,
August 2025 in “Drug Delivery and Translational Research” This review discusses lipid-polymer hybrid nanoparticles for dermatological applications, outlining their structural and formulation advancements, but reports no new clinical results and calls for further research on their therapeutic potential.
5 citations
,
May 2020 in “Pharmaceutical Research” This study found that short durations of heat and specific chemical penetration enhancers significantly improved the delivery of finasteride to human scalp skin and hair follicles.
5 citations
,
August 2018 This paper highlights the growing scientific interest in plant extracts for cosmetics due to their potential benefits, including antioxidant, antimicrobial, and protective properties, while emphasizing the need for quality and safety assessment to mitigate possible adverse reactions.
5 citations
,
June 2015 in “Journal of Investigative Dermatology” This review discusses the use of the feather model to explore tumorigenesis, regeneration, and hormone-dependent growth, highlighting its potential for advancing biomedical research, but reports no novel experimental results.
4 citations
,
January 2020 in “Frontiers in Physiology” This review discusses molecular signaling pathways and nutritional factors influencing feather growth and regeneration in poultry and offers no new results; the authors suggest these insights may guide strategies for producing superior plumage.
3 citations
,
October 2022 in “PloS one” This study developed a method to culture and maintain chicken feather follicles in vitro, preserving structure and biology similar to their in vivo state, though some gene expression was altered.
2 citations
,
April 2019 in “Experimental Dermatology” The article concludes that studying how skin forms is key to understanding skin diseases and improving regenerative medicine.
1 citations
,
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that centrosome ablation in developing epidermis triggers cell surveillance pathways, resulting in thinner skin and halted hair follicle growth, while later stages of epidermal growth may operate independently of basal progenitor division orientation.