research Cytostatics and Immunosuppressive Drugs: Toxicities and Management
Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.
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research Molecular Basis of Hair Follicle Donor Dominance in Androgenetic Alopecia and Sexual Dimorphism of the Skin
Hair loss patterns differ between males and females due to 5 master regulators and JAK-STAT signaling affects hair growth.
research A Systematic Simulation-Based Meta-Analytical Framework for Prediction of Physiological Biomarkers in Alopecia
The study identified 12 potential biomarkers for hair loss and how they affect hair growth.
research The Protease Corin Regulates Electrolyte Homeostasis in Eccrine Sweat Glands
Corin helps control salt and sweat release in sweat glands.
research iTRAQ-Based Quantitative Proteomics Revealing the Therapeutic Mechanism of a Medicinal and Edible Formula YH0618 in Reducing Doxorubicin-Induced Alopecia by Targeting Keratins and TGF-β/Smad3 Pathway
YH0618 helps reduce chemotherapy-induced hair loss by targeting specific proteins and pathways.
research Androgenetic Alopecia: The Use of Minoxidil and Its Adverse Effects
Minoxidil is effective and safe for hair growth in Androgenetic Alopecia, with manageable side effects.
research Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa
Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.
research Temporary Relocation During Rest Periods: Relocation Stress and Other Factors Influence Hair Cortisol Concentrations in Horses
Moving horses to new places can increase their stress levels, as shown by higher stress hormone in their hair.
research Guava Leaf Extract as Bioactive Substances for Anti-Androgen and Antioxidant Activities
Guava leaf extract may help treat hair loss and protect cells by blocking certain genes and fighting damaging molecules.
research Soy Protein Containing Isoflavones Improves Facial Signs of Photoaging and Skin Hydration in Postmenopausal Women: Results of a Prospective Randomized Double-Blind Controlled Trial
Soy protein with isoflavones reduces wrinkles and improves skin hydration in postmenopausal women.
research Matricellular Proteins in the Homeostasis, Regeneration, and Aging of Skin
Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
research Two Mutations at KRT74 and EDAR Synergistically Drive the Fine-Wool Production in Chinese Sheep
Two mutations in KRT74 and EDAR genes cause sheep to have finer wool.
research Connarus Semidecandrus Jack Exerts Anti-Alopecia Effects by Targeting 5α-Reductase Activity and an Intrinsic Apoptotic Pathway
Connarus semidecandrus Jack extract promotes hair growth and thickness, reduces prostate cancer cell growth, and could potentially be used as a treatment for hair loss.
research Dermatologic Manifestations of Mitochondrial Dysfunction: A Review of the Literature
Mitochondrial dysfunction is linked to various skin conditions and could be a target for treatments.
research The Role of Androgens in Androgenetic Alopecia Associated with the Severity of COVID-19
Androgens play a key role in causing alopecia by changing the hair growth cycle.
research Genetic Screening of Non-Classic CAH Females with Hyperandrogenemia Identifies a Novel CYP11B1 Gene Mutation
A new mutation in the CYP11B1 gene was found in a woman with mild hyperandrogenemia, a rare cause of non-classic congenital adrenal hyperplasia.
research Pathology of Mouse Models of Accelerated Aging
Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
research Proanthocyanidins from Grape Seeds Promote Proliferation of Mouse Hair Follicle Cells In Vitro and Convert Hair Cycle In Vivo
Grape seed proanthocyanidins can promote hair growth.
research Ethnodermatological Use of Medicinal Plants in India: From Ayurvedic Formulations to Clinical Perspectives – A Review
Indian herbal medicine shows promise for treating skin diseases but needs more research to prove effectiveness.
research Thiazole: A Versatile Standalone Moiety Contributing to the Development of Various Drugs and Biologically Active Agents
Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.
research The Potential of Clausena Anisata (Willd.) Hook.f. ex Benth Against Propionibacterium Acnes
Clausena anisata may be effective in treating acne due to its ability to fight bacteria, reduce inflammation, and possibly lower sebum production.
research Evo Devo of the Vertebrate Integument
The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
research Traditional Uses of Medicinal Plants in Their Conservation in Charmang Village, Bajaur, KP, Pakistan
Using medicinal plants traditionally helps in their preservation in Charmang Village, Pakistan.
research Effects of Bioactive Composition in Oryza Sativa L. Cv. KDML105 Bran Extract on Gene Expression Related to Hair Cycle in Human Hair Follicle Dermal Papilla Cells
KDML105 bran extract may help with hair growth and prevent hair loss.
research Clinical Efficacy of Topical or Oral Soy Supplementation in Dermatology: A Systematic Review
Soy supplements improve various skin conditions and aging signs, with topical use boosting skin barrier function.
research Nutraceuticals for Androgenetic Alopecia
Nutrafol® and Viviscal® can slightly help hair growth in hair loss.
research South Asian Epidemic of Antifungal Therapeutic Failures: Congress Proceedings and Take-home Messages. First International Congress of SAARCUM: South Asian Alliance Against Recalcitrant Cutaneous Mycosis. 17 November 2018, Medanta – The Medicity, Gurugram, India
The congress concluded that misuse of antifungal drugs in South Asia has led to widespread treatment failure, and new approaches and regional cooperation are needed.
research High-Throughput Sequencing Reveals miRNAs Affecting Follicle Development in Chicken
Certain miRNAs are linked to chicken feather development.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression
Tadalafil and Finasteride may help treat aggressive melanoma.
research Abstracts From The 55th European Society Of Human Genetics Conference: E-Posters
Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.