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MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

FOL-026 peptide can help repair blood vessels and promote growth, offering potential treatment for vascular diseases.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.

SCD1 is crucial for skin health and overall energy balance.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

Blocking the ATX-LPA pathway may improve insulin sensitivity and mitochondrial function in obesity.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.

Different types of PCOS need specific diagnosis methods and treatments.

The enzyme sEH is important for hair growth and its inhibition could help treat hair loss.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Eating a Mediterranean diet and taking certain supplements may improve symptoms of PCOS.

Insulin resistance is a complex condition that can lead to many diseases and has few treatment options.

PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.