February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, the researchers found that KAP3.1, KRTAP 8-1, and KRTAP 24-1 genes positively correlated with the growth cycle of cashmere in Inner Mongolia goats, aligning with the observed hair cycle phases.
January 2011 in “China Animal Husbandry & Veterinary Medicine” This study examined the effects of constant-release melatonin on the SOX21 gene in Inner Mongolia Cashmere goats, finding that it stabilized gene expression and reduced stress responses with notable expression changes except in March, April, and May.
In this study, RNA-sequencing identified differentially expressed genes, including FGF5, FGFR1, and RRAS, that affect the hair follicle growth cycle in Inner Mongolian Cashmere goats.
55 citations
,
February 2014 in “Journal of Structural Biology” This study observed that human hair macrofibrils predominantly exhibit a double-twist architecture with varying inter-macrofibril angles, advancing insights into their structural organization and mechanical implications.
108 citations
,
October 2005 in “Journal of Ultrasound in Medicine” This study found that ultrasonography improved preoperative diagnosis rates of pilomatricoma to 76% by identifying specific features such as inner echogenic foci and a peripheral hypoechoic rim.
25 citations
,
July 2015 in “EMBO Reports” This study suggests that mouse lineage specification during pre-implantation development involves distinct timing and mechanisms for trophectoderm and inner cell mass differentiation, challenging existing models.
August 2026 in “Women s Health” This preliminary pilot study found that a combined microneedling-assisted Panax ginseng exosome protocol with adjunctive inner gel use led to short-term improvements in patient-reported vulvovaginal symptoms and qualitative improvements in vulvar skin tone, though results are preliminary and based on a small, uncontrolled sample.
March 2025 in “Animal Bioscience” In this study, researchers conducted a whole-transcriptome analysis of Dazu Black Goats and Inner Mongolia Cashmere Goats to explore differences in hair follicle development and melanin production, revealing variations in hair characteristics and 640 differentially expressed RNAs that could inform goat breeding and textile applications.
October 2021 in “Research Square (Research Square)” This study found that gene expression patterns can effectively distinguish the cashmere growth cycle stages and highlight molecular pathways, suggesting melatonin's role in regulating cashmere growth in Inner Mongolian goats.
April 2019 in “Journal of Investigative Dermatology” This study reported that gain-of-function mutations in TRPV3 lead to hair loss in mice by disrupting inner root sheath keratinocyte differentiation, ultimately causing follicular keratinocyte stem cell exhaustion and permanent follicle disruption.
December 2022 in “IntechOpen eBooks” This paper discusses forensic DNA phenotyping, emphasizing its ability to infer visible traits from biological samples without reference samples, but notes ethical and legal concerns related to its use.
54 citations
,
January 2009 in “British Journal of Dermatology” This study found that in scarring alopecia, stem cells are differentially localized, suggesting that both inner and outer root sheath stem cells, rather than just follicular bulge stem cells, are involved.
2 citations
,
July 2021 in “Annales De Dermatologie Et De Venereologie” In this study, isotretinoin provided complete remission in some patients with vulvar Fordyce adenitis, a condition causing painful recurrent lesions on the labia minora and inner labia majora.
January 2026 in “Animal Advances” In this study of four Chinese goat breeds, black goats exhibited significantly higher melanin content, while Inner Mongolian cashmere goats had longer fiber lengths. These findings highlight genetic variations in coat color and fiber length, informing future breeding programs.
November 2025 in “Biomedicine & Pharmacotherapy” This study found that administering calcium blockers verapamil or nimodipine significantly preserved auditory function and hair cell survival in Cx26-cKO mice, suggesting potential protective effects for other inner ear disorders.
This study observed that spiritual well-being significantly correlates with quality of life aspects in newly diagnosed Palestinian women with breast cancer, where factors like inner peace and faith predicted better body image and reduced distress from hair loss.
December 2021 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that knocking out the Hars2 gene in mouse cochlear hair cells led to mitochondrial dysfunction and ROS stress, resulting in progressive hearing loss and differential effects on inner and outer hair cells.
In this study of mouse hair follicles, Raptor was specifically expressed in hair follicle stem cells, while Rictor was mainly found in inner root sheath cells, indicating distinct roles in hair growth stages.
April 2019 in “Journal of Investigative Dermatology” In this study, engineered mice with a mutation similar to that in Olmsted syndrome showed progressive hair loss due to impaired inner root sheath keratinocyte differentiation and stem cell exhaustion.
This study found that hair fibers broke down and lost keratin in extremely basic conditions, revealing the inner medulla and changing the color of the fibers.
9 citations
,
July 2025 in “Pharmaceuticals” This review highlights the therapeutic potential of plant-derived exosomes, noting their larger size compared to animal-derived exosomes and usefulness in targeted drug delivery and inter-kingdom communication. It summarizes existing research on their biogenesis, characterization, and engineering for drug delivery, indicating significant opportunities for biotechnological advancements.
8 citations
,
August 2014 in “Biochemical and Biophysical Research Communications” The study found that over-expressing ornithine decarboxylase in the outer root sheath of the hair follicle in mice increases UVB-induced tumor growth and invasive squamous cell carcinoma compared to inter-follicular epidermal keratinocytes.
6 citations
,
March 2021 in “Journal of the American Academy of Dermatology” This study found that the Brigham Eyelash Tool for Alopecia (BELA) is a reliable measure for assessing eyelash loss in alopecia areata patients, demonstrating high inter- and intrarater reliability.
6 citations
,
December 2018 in “International Journal of Cosmetic Science” In this study, hair samples from Mexican women were found to be intermediate in diameter and shape between Asian and Caucasian hair, exhibiting high intra- and inter-individual variability and unexpected levels of tensile damage.
4 citations
,
April 2021 in “Experimental Dermatology” This study shares preliminary findings that roxithromycin treatment tendentially increased hair shaft production and altered the hair follicle microbiota in human hair ex vivo, with substantial inter-individual differences observed.
May 2026 in “British Journal of Clinical Pharmacology” In this study, researchers observed low variability in hair formoterol concentrations for COPD patients with stable adherence, but inter-patient differences and other factors may limit the effectiveness of hair analysis as a reliable tool for assessing medication adherence.
June 2025 in “British Journal of Dermatology” In this study, a daily low-dose regimen of oral minoxidil and finasteride over 12 months led to significant hair density improvements in over 92% of adult men with androgenetic alopecia, including those with advanced stages, though inter-rater reliability in photo assessments was modest.
December 2024 in “eCommons - AKU (Aga Khan University)” This study concluded that the platelet rich plasma injectable competency assessment tool (PICAT) demonstrated strong validity, internal consistency, and inter-rater reliability for evaluating dermatology residents at PNS Shifa Hospital.
46 citations
,
October 2009 in “Archives of Dermatology” This study found that loose anagen hair syndrome is a common form of alopecia in young girls, typically presenting with thin, sparse hair and usually confirmed by a hair-pull test.
12 citations
,
December 2020 in “Archives animal breeding/Archiv für Tierzucht” This study found that EDA and EDAR are expressed throughout cashmere goat fetal development and play a critical role in hair follicle formation by influencing gene expression in fibroblasts and epithelial cells.