Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that women with negative or mixed feelings about Botox and facial fillers reported diverse and sometimes persistent physical and psychological impacts, feeling commodified, fractured, abandoned, reflective, and transformed.

This study demonstrated that a newly developed polypeptide-protein hydrogel with vascularization and antibacterial properties promoted tissue regeneration and hair follicle formation in infected wound healing.

In this study, among 2,000 patients with alopecia universalis, mesotherapy combined with systemic treatments like BMI, JAK inhibitors, and adalimumab showed the highest success in hair regrowth, particularly for children, with the combination therapy group achieving a 42% positive response rate.

This study introduced hydrogel microneedles loaded with palladium nanoparticles, which utilize the inherent cytotoxicity of polyethyleneimine to enhance the effectiveness of doxorubicin in treating melanoma, achieving a tumor inhibition rate of up to 98% in a murine model.

In this study, researchers developed a new microneedle patch delivery system for minoxidil, which enhanced its controlled release and improved hair growth in mice, potentially offering better treatment outcomes for androgenetic alopecia.

This study investigated the impact of container-tip design and hair density on the scalp delivery of minoxidil in topical formulations, finding that higher hair density reduced delivery, particularly with larger tip containers, indicating the importance of these factors in product design.

This study suggests that PGD2 may increase testosterone production in keratinocytes through oxidative stress pathways, with n-acetyl-cysteine blocking this effect.

This study suggests that nanotechnology-based drug delivery systems can improve the targeted, sustained delivery and stability of dermatological treatments, potentially leading to better outcomes and reduced side effects for various aesthetic skin conditions, though further clinical trials are needed to confirm these benefits.

This study found that a combination of betulin and cytostatic Namitecan had a statistically significant synergistic effect on solid Ehrlich adenocarcinoma tumors in NMRI mice, and suggests a promising method for administering betulin in in vivo experiments despite its water insolubility.

This review discusses the enhancement of drug penetration through hair follicles and reports no new clinical results while noting the potential for future research on controlled drug release methods.

New drugs for Alzheimer's and rheumatoid arthritis advanced, a Zika vaccine is in development, and there were business deals in anesthesia and oncology.

This study found that finasteride-loaded microemulsions using poloxamer 124 significantly enhanced skin penetration of the drug compared to a standard solution, primarily through targeting hair follicles via the transfollicular pathway, with intercluster, intercellular, and transcellular pathways contributing less.

In this pilot study, patients with atrophic acne scars experienced clinical improvements and high satisfaction after receiving three biweekly microinfusions of human insulin into their skin.

This abstract notes a disclaimer about supporting information and does not report new research findings.

This study observed that smaller polymeric submicron particles provided more efficient selective drug delivery to inflamed skin in a mouse model, enhancing therapeutic effects while reducing systemic adverse effects.

This case report describes a 45-year-old male who developed a post-operative infection after hair transplantation, likely due to the reuse of a dull sterile implanter pen, highlighting the need for proper instrument selection and infection control.

In this study, researchers highlighted that emulgels, a combination of emulsions and gels, offer a novel topical delivery method for hydrophobic drugs, possessing attributes such as easy spreadability and bio-friendliness, making them suitable for conditions like acne, fungal infections, and psoriasis.

A new microneedle system may improve hair loss treatment by delivering ketoconazole directly to hair follicles.

In this study, pneumatic injections of non-cross-linked hyaluronic acid were associated with improvements in skin texture, pores, wrinkles, and transepidermal water loss in healthy female volunteers.

This review highlights that direct drug delivery to the lungs for treating lung cancer may offer more precise targeting while reducing side effects compared to traditional methods.

This study found that while hyaluronic acid fillers can enhance facial balance and aesthetics, particularly in the temple area, they carry significant risks like vascular occlusion and blindness, highlighting the need for careful technique and product selection to ensure safety.

This review highlights the potential of microneedles and nanomedicine in advancing tissue regeneration, emphasizing their innovative, localized, and minimally invasive approaches as promising solutions to current challenges in treating chronic wounds and degenerative diseases.

In this study, injectable platelet-rich fibrin (i-PRF) was found to enhance the proliferative, migratory, and hair-inducing abilities of dermal papilla cells more effectively than platelet-rich plasma through the TGF-β/Smad pathway.

This study reported that autologous whole fat injection in the scalp considerably increased hair growth in patients with androgenetic alopecia.

This study found that using uniform poly(lactic-co-glycolic) acid microspheres to deliver insulin-like growth factor 1 stabilizes the protein and enhances its sustained delivery, supporting stem cell functions comparably to traditional methods, and showing potential for tissue and organ regeneration.

This article reviews triamcinolone acetonide as an intramuscular long-acting steroid therapy for dermatologic disorders but reports no new clinical results.

This study developed a hydrogel from glycol chitosan and silica nanoparticles, which showed promise in wound healing by supporting microvessel and hair follicle growth in skin defects.

This study found that intrathymic injection of recipient-type splenocytes into donor rats, combined with antilymphocyte antiserum, effectively prevented graft-versus-host disease for up to 300 days.

This study found that smaller mesoporous silica particles (400-600 nm) accumulated in skin furrows, suggesting their potential as carriers for enhancing the delivery of topical medications like metronidazole.

This review discusses the potential of microneedles in cancer diagnosis and treatment, highlighting advances and ongoing clinical trials, but reports no new results; it emphasizes the minimally invasive nature of this technology.