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Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Some herbs show promise as antiandrogenic agents.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Finasteride doesn't harm bone density in older men with BPH.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Finasteride may affect PNMT, causing side effects.

Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.

Eclipta alba extract could be a promising natural treatment for hair loss.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Certain drugs that block specific enzymes can help treat prostate diseases.

Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.

Using 5-alpha reductase inhibitors may increase the risk of mild depression.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Some Thai plants, especially Carthamus tinctorius, could help prevent hair loss and promote hair growth without adverse effects.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Finasteride exposure harms tadpole reproduction and hormone balance.

Oral finasteride and dutasteride may negatively affect erectile function in rats.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

Both drugs lower DHT levels, with GI198745 being more effective.

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Finasteride helps reduce pain and inflammation in animals.