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The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Some medicinal plants can help heal wounds and may lead to new treatments.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Male pattern hair loss could hint at androgens affecting COVID-19 severity.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Zinc is crucial for nutrition, especially in patients with specific health conditions, and requires careful supplementation and monitoring.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

No treatment fully prevents hair loss from chemotherapy yet.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Skin fat helps with body temperature control and has other active roles in health.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Correcting nutrient deficiencies may help with hair loss, but the benefits of supplements without a deficiency are uncertain and could be harmful.