18 citations
,
March 2004 in “Clinics in Dermatology” This review discusses recent advances in understanding the cellular, molecular, and genetic factors contributing to lupus erythematosus and reports no new experimental findings.
1 citations
,
December 2010 in “The journal of small animal practice/Journal of small animal practice” This article discusses hair loss disorders in domestic animals, but it contains no abstract or new research findings.
This narrative review highlights the potential of exosomes in regenerative and aesthetic dermatology, particularly in India, but emphasizes that their clinical use is still investigational due to limited and diverse study data, insufficient long-term safety information, and regulatory challenges.
January 2026 in “Acta Dermatovenerologica Alpina Pannonica et Adriatica” In this study, cicatricial alopecias were classified by inflammatory cell type and the researchers highlighted that primary cicatricial alopecia's exact causes remain unknown, accounting for 6% of all hair diseases despite its unclear prevalence.
January 2024 in “Ankara City Hospital Medical Journal” This case report describes a 42-year-old woman with Rhupus, a rare overlap syndrome of rheumatoid arthritis and systemic lupus erythematosus, highlighting challenges in diagnosis due to non-specific clinical criteria and documenting specific symptoms such as inflammatory arthritis, malar rash, and hematological abnormalities observed during follow-up.
July 2023 in “Clinical, cosmetic and investigational dermatology” In this study, reflectance confocal microscopy was used to diagnose periorificial dermatitis, revealing specific skin changes such as hair follicle dilatation, increased vascular density, and inflammation, which help distinguish it from similar conditions.
April 2021 in “Journal of Investigative Dermatology” This study suggests that rather than inhibiting IL-15, selectively stimulating IL-15Ra-mediated signaling could be beneficial for managing alopecia areata and possibly other inflammatory hair loss conditions, as IL-15 promoted hair growth and maintained immune privilege in human hair follicles.
April 2012 in “Informa Healthcare eBooks” Classifying hair diseases, like alopecia, is difficult and needs more research to understand their causes.
1 citations
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July 2022 in “Functional foods in health and disease/Journal of functional foods in health & disease” This study found that oral probiotic supplementation over 12 weeks may improve hair growth, skin condition, metabolic health, and stress responses in Chinese adults with hair loss and a high risk of metabolic syndrome.
February 2026 in “Eduvest - Journal Of Universal Studies” This review discusses the molecular mechanisms and therapeutic effectiveness of Janus Kinase Inhibitors for inflammatory skin diseases, suggesting these inhibitors have a rapid onset and favorable safety profile compared to conventional treatments.
18 citations
,
October 2017 in “PLOS ONE” This study found that in Pomeranians with Alopecia X, key genes in the Wnt and Shh signaling pathways and stem cell markers are downregulated, which may explain the absence of anagen hair follicles.
6 citations
,
August 2006 in “Journal of Cutaneous Pathology” This case report describes two brothers with an unusual, possibly treatment-resistant inflammatory variant of androgenic alopecia, featuring follicular isthmic lymphocytic inflammation and diffuse central scalp hair loss.
759 citations
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February 2009 in “Current Biology” This review summarizes fundamental concepts and recent advancements in hair follicle biology, including insights from mouse models into broader molecular and cellular processes relevant to regeneration and development.
349 citations
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January 2005 in “The FASEB journal” This review discusses the cutaneous serotoninergic/melatoninergic system's potential role in skin function and resilience against environmental and internal stresses, but does not report new experimental findings.
290 citations
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December 2017 in “Journal of The American Academy of Dermatology” This article reviews the epidemiology, clinical evaluation, and pathogenesis of alopecia areata and highlights recent advancements, but it does not report new clinical findings.
271 citations
,
September 2008 in “Nutrition reviews” This study identified new dietary ligands for the human vitamin D receptor, including curcumin and gamma-tocotrienol, which may influence its biological functions.
236 citations
,
July 2001 in “Trends in Molecular Medicine” This review discusses common hair loss conditions and explores how advancements in hair follicle biology might lead to more effective treatments but reports no new results.
234 citations
,
December 1996 in “Journal of The American Academy of Dermatology” The authors concluded that chronic telogen effluvium in middle-aged women presents distinct clinical and histological features that differ from androgenetic alopecia and acute telogen effluvium.
214 citations
,
March 1993 in “Archives of Dermatology” This article proposes five different mechanisms for telogen effluvium, supported by clinical findings, based on changes in different phases of the hair cycle.
192 citations
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April 2019 in “ACS nano” In a mouse model, this study demonstrated that a microneedle patch system using keratin and integrated with MSC-derived exosomes and UK5099 promoted hair regrowth more efficiently than traditional delivery methods.
163 citations
,
April 2019 in “Nature Communications” This study found that mechanical skin stretching can stimulate hair stem cell proliferation and hair regeneration by activating a complex pathway involving WNT, BMP-2, and M2 macrophages.
160 citations
,
March 2009 in “Seminars in Cutaneous Medicine and Surgery” This article reviews lichen planopilaris, its presentation, and treatment challenges, and emphasizes the need for more research into its pathogenesis and therapy efficacy; it reports no new findings.
159 citations
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November 2007 in “American Journal of Pathology” In this study, researchers found that substance P triggered premature catagen development and immune changes in human scalp hair follicles, providing a possible biological link between stress and hair loss conditions like telogen effluvium and alopecia areata.
159 citations
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July 2006 in “Endocrine Reviews” This article discusses the influence of estrogens on hair follicle growth and metabolism, suggesting a significant role alongside androgens in hair growth control but reports no new clinical results.
158 citations
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February 2000 in “Archives of dermatology” This study reports that some patients with androgenetic alopecia may also exhibit clinical and histological features of inflammation and fibrosis, similar to those found in lichen planopilaris.
139 citations
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February 2014 in “Journal of Advanced Research” This review explores the impact of vitamin D deficiency on the skin from a dermatological perspective, but reports no new clinical results.
139 citations
,
July 1991 in “Journal of The American Academy of Dermatology” This article discusses the structure of hair follicles and their significance in evaluating hair disorders, but it does not report any new research findings.
127 citations
,
January 2015 in “Journal of Biological Rhythms” This review discusses the role of the circadian clock in skin functions such as cell proliferation and UV protection and reports no new results; the authors note its potential in studying immune regulation and seasonal behaviors.
124 citations
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June 2020 in “Cell Stem Cell” This study found that in mice, dermal adipocytes initiate inflammation and aid repair after skin injury by releasing lipids, suggesting a role in managing inflammatory diseases and impaired wound healing.
109 citations
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December 2003 in “American Journal of Pathology” This study observed that the ontogenetic transition from scarless repair in early fetal rat wounds to scar-forming repair in late gestation is associated with differential TGF-β ligand and receptor expression patterns.