Navigating Rhupus Complexity

Rhupus is a rare syndrome that combines features of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), with only about 60 cases reported in the literature. This document discusses a 42-year-old female patient with Rhupus who exhibited symptoms such as inflammatory arthritis, severe malar rash, oral ulcers, alopecia, anemia, and thrombocytopenia. Her laboratory results showed elevated erythrocyte sedimentation rate, low hemoglobin, and low platelet count. The case highlights the diagnostic challenges due to the lack of well-defined clinical criteria and aims to contribute to the understanding of this complex syndrome.