43 citations
,
May 2011 in “Dermatologic Therapy” This article discusses the phases and histological features of alopecia areata and reports no new clinical findings; the authors emphasize recognizing these phases for accurate diagnosis.
42 citations
,
October 2011 in “Seminars in Cell & Developmental Biology” This review explores the role of Eph receptors and ephrins in skin cell processes, discussing their potential for therapeutic targeting in dermatological disorders, but it presents no new research findings.
41 citations
,
September 2003 in “Journal of Investigative Dermatology” This study suggests that the COX-2 enzyme plays a role in hair follicle biology, as transgenic overexpression in mice induced hair follicle cycling disturbances and alopecia, which was mitigated by COX-2 inhibition.
38 citations
,
October 1988 in “Clinics in Dermatology” Minoxidil can help grow hair and make hair follicles bigger, but it can also cause side effects.
30 citations
,
December 2001 in “Journal of The European Academy of Dermatology and Venereology” This paper discusses hormonal therapy options for women with severe acne, focusing on treatment for cases that do not respond to conventional methods, but it reports no new clinical findings.
28 citations
,
March 2016 in “Toxicologic pathology” This review discusses the function and pathology of hair follicles and highlights the potential of using dogs as a model to study human hair and stem cell disorders, but presents no new experimental results.
22 citations
,
February 2017 in “Clinical and Experimental Dermatology” This study suggests that icariin promotes hair follicle growth in mice by enhancing IGF-1 expression in dermal papilla cells.
22 citations
,
November 2007 in “Journal of Investigative Dermatology Symposium Proceedings” This presentation reviews recent discoveries about signaling mechanisms in hair follicles and their potential influence on hair cycle control and melanogenesis, without presenting new experimental results.
17 citations
,
January 2011 in “Skin Research and Technology” Hair from people with seborrheic dermatitis is thicker scaled, more damaged, and thinner than healthy hair, and atomic force microscopy can help monitor the condition.
14 citations
,
August 2018 in “Frontiers in Cellular and Infection Microbiology” This study found that dengue virus infection caused inflammation and cell death in human hair-follicle dermal papilla cells, which may contribute to increased hair shedding observed during the epidemic in Taiwan.
14 citations
,
September 2016 in “Journal of Cutaneous Pathology” This review discusses the classification and diagnosis of primary scalp alopecia, focusing on scarring and non-scarring types, and reports no new clinical results; it emphasizes simplified diagnostic pathways and tissue processing techniques.
14 citations
,
April 2014 in “International Journal of Cosmetic Science” This article discusses the multifactorial etiopathogenesis of acne vulgaris, highlighting the roles of sebum production, keratosis, bacterial development, and inflammatory mediators, but reports no new clinical results.
13 citations
,
April 2013 in “Immunotherapy” This article discusses the potential of phospholipase A2 inhibition as a therapeutic strategy for inflammatory skin diseases and emphasizes the need for further exploration of its role and administration methods.
12 citations
,
January 2005 in “Journal of Cosmetic Dermatology” This review discusses the natural progression of androgenetic alopecia and potential factors influencing its long-term prognosis, reporting no new clinical results.
11 citations
,
February 2021 in “Biomedicines” This review discusses the role of hair follicle bacterial colonization in immune responses and the pathogenesis of alopecia but reports no new clinical results.
9 citations
,
December 2021 in “Molecules” This study found that certain metabolites from the plants Bidens pilosa, Calophyllum inophyllum, and Fagraea berteroana may support hair follicle growth by promoting dermal papilla cell proliferation, supporting their traditional use in hair care.
9 citations
,
February 2018 in “Journal of The American Academy of Dermatology” This study found that methylene blue staining helped identify late catagen and telogen hair follicles more accurately than unstained follicles, which suggests that established telogen percentage standards may be overestimated.
8 citations
,
October 2016 in “Experimental dermatology” This paper proposes that the induction of HF-specific neo-antigens by peripheral CD8+ T cells may maintain self-tolerance but could also lead to immunopathology in conditions like alopecia areata.
7 citations
,
April 2020 in “Dermatologic Therapy” In this study, nine male cases of androgenetic alopecia showed marked improvement after receiving systemic dexpanthenol treatment.
7 citations
,
February 2018 in “Journal of Investigative Dermatology” This study investigates the role of peroxisome proliferator-activated receptor gamma in hair follicle morphogenesis using a novel mouse model but reports no new results, highlighting the need for further research on its function during the hair cycle.
7 citations
,
December 2004 in “Medicine” This article reviews the anatomy and pathology of skin and hair to aid in diagnosing skin diseases and discusses potential therapies, without reporting new clinical results.
6 citations
,
April 2025 in “Communications Biology” In this study, researchers used a murine model of irritant contact dermatitis to reveal that hair follicle regions serve as key sites for neutrophil transepidermal migration, which requires MMP-9 expression stimulated by dermal monocytes.
6 citations
,
October 2016 in “Journal of Cellular Physiology” This study found that human dermal fibroblasts can promote the viability and proliferation of microvascular endothelial cells in vitro, revealing important interactions at play in hair growth.
4 citations
,
May 2025 in “Frontiers in Immunology” This review examines the mechanisms of Janus kinase inhibitors in treating alopecia areata and evaluates their efficacy and safety, but reports no new clinical results.
3 citations
,
March 2021 in “JAAD case reports” This case report describes a 40-year-old man whose vitiligo and psoriasis responded favorably to ixekizumab after experiencing vitiligo onset and psoriasis relapse during adalimumab treatment.
3 citations
,
October 2020 in “Internatuinal Journal of Radiation Research” This study reports that γ-ray exposure in rats led to dermal endothelial proliferation, new vessel formation around hair follicles, and increased inflammatory markers, suggesting possible early stimulatory effects on hair growth.
2 citations
,
October 2025 in “Discover Immunity.” This review discusses the classification, diagnosis, and potential treatment pathways for Alopecia Areata, emphasizing the complex genetic and immunological factors involved, but reports no new clinical results.
2 citations
,
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that stem cells can temporarily act as non-professional phagocytes during hair cycle regeneration by clearing apoptotic cells through a process requiring local lipids and retinoids for activation, providing insights into their dual role in maintaining tissue integrity.
2 citations
,
March 2020 in “Cell” This article reviews Elaine Fuchs’ groundbreaking discovery of adult skin stem cells' roles in homeostasis, wound repair, inflammation, and cancer, and reports no new results.
2 citations
,
November 2011 in “InTech eBooks” This article reviews the types and characteristics of adrenal cortex tumors, including their hormone secretion and detection as incidental findings, but presents no new research results.