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Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Stronger corticosteroids cause more skin damage in hairless dogs, similar to effects in humans.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.

Minoxidil may protect nerves and improve hair quality during paclitaxel treatment.

People with alopecia areata have higher levels of a heart disease marker than those without hair loss.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Hormones and genes affect hair growth and male baldness.

Korean Red Ginseng may improve skin condition and reduce allergy markers in atopic dermatitis patients.

Mouse stem cells from hair follicles can improve wound healing and reduce scarring.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.

Malondialdehyde-modified DNA may trigger an immune response in alopecia areata patients.

A 14-year-old girl with severe hair loss regrew her hair using upadacitinib.

People with certain types of alopecia have a slightly higher risk of cancer, especially thyroid, bladder, and prostate cancers.

Low IGF-1 and high HDL cholesterol levels are linked to more hair loss in middle-aged women.

Smoking is linked to more hair loss and premature graying compared to nonsmokers.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

People with hidradenitis suppurativa often have lower vitamin D levels, weaker hip bones, and altered bone metabolism markers.

The document explains the difficulty in diagnosing and treating brain diseases caused by the immune system and stresses the need for quick and accurate tests.

Oxidative stress may contribute to hair loss in alopecia areata and antioxidants could potentially help as a treatment.

JAK inhibitors for alopecia areata are linked to minor side effects like headache and acne, but not to an increased risk of serious adverse events.

IMA and IMA/albumin levels don't predict alopecia areata severity.

Women with PCOS have lower adiponectin hormone levels and are more likely to have insulin resistance.

Longer TA repeats in the SRD5A2 gene may increase acne risk in Chinese people.

Tofacitinib, a JAK inhibitor, improved hair regrowth in most patients with severe alopecia areata and had minimal side effects.

The health of the gut may be important in developing new ways to prevent, diagnose, and treat alopecia areata.