271 citations,
May 2019 in “Cells” The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.
185 citations,
February 2018 in “Journal of Investigative Dermatology” Melatonin may benefit skin health and could be a promising treatment in dermatology.
160 citations,
January 2017 in “Development” Blood vessels and specific genes help turn cartilage into bone when bones heal.
143 citations,
September 2008 in “Experimental gerontology” Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
119 citations,
October 2011 in “Journal of Veterinary Internal Medicine” Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.
114 citations,
February 2012 in “International Journal of Dermatology” Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
89 citations,
January 2009 in “Advances in Clinical Chemistry” Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
69 citations,
December 2015 in “Journal of Controlled Release” Nanocapsules can improve clobetasol delivery to hair follicles, reducing side effects.
67 citations,
February 2015 in “Life Sciences” Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.
47 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Premature graying of hair may suggest health issues and currently lacks effective treatments.
46 citations,
March 2019 in “Journal of Pineal Research” Melatonin improves cashmere goat hair growth and quality by increasing antioxidants and reducing cell death.
43 citations,
June 2016 in “Clinics in Plastic Surgery” The conclusion is that fat grafting is safe and effective but carries risks that need careful management.
38 citations,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
33 citations,
September 2016 in “Lasers in Surgery and Medicine” Fractional resurfacing is safe and effective for certain skin conditions in Asian patients, but care must be taken to avoid skin pigmentation issues.
32 citations,
February 2019 in “Journal of neurochemistry” Sex hormones affect brain injury differently in males and females.
30 citations,
June 2017 in “Talanta” MALDI Imaging Mass Spectrometry is a useful method for studying skin conditions, but sample preparation is crucial for accurate results.
27 citations,
July 2018 in “Journal of optometry” Eyelashes protect the eyes, but more research is needed to understand how.
21 citations,
April 2011 in “Physiological Research” Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.
19 citations,
October 2017 in “European Journal of Pharmaceutics and Biopharmaceutics” The gel made of minoxidil and hydroxypropyl-β-cyclodextrin improves hair growth and is good for long-term use.
18 citations,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
17 citations,
June 2019 in “Cellular signalling” Minoxidil helps protect and rebuild elastic fibers in arteries, improving artery function, especially in older females.
16 citations,
February 2019 in “Pediatric Blood & Cancer” Most children with CNS tumors on targeted therapy had skin reactions, which were generally treatable without stopping the therapy.
14 citations,
October 2012 in “Clinics in Plastic Surgery” Adding stem cells to fat grafts for facial rejuvenation might improve outcomes, but more research is needed to confirm safety and effectiveness.
13 citations,
June 2020 in “Scientific reports” Melatonin stimulates the skin components of ram's scrotum during their non-breeding season.
12 citations,
March 2016 in “BBA clinical” Increased Toll-like receptors in blood cells may contribute to alopecia areata and could be a target for new treatments.
7 citations,
June 2021 in “Amino acids” Human hair protein modifications could potentially indicate heart disease risk.
7 citations,
February 2021 in “Dermatologic Therapy” Sebaceous glands are involved in various skin disorders, some treatable with medications like finasteride and minoxidil.
6 citations,
May 2022 in “Research and reports in urology” Caesalpinia bonduc seed extracts may help treat enlarged prostate in rats.
3 citations,
August 2021 in “Uro” Saw palmetto may improve urinary symptoms with fewer sexual side effects compared to some medications.
2 citations,
November 2023 in “Curēus” Platelet-rich plasma (PRP) speeds up skin wound healing and has potential in medical and cosmetic uses.