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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.

Collagen XVII is important for skin aging and wound healing.

SGK3 is essential for proper hair growth and health.

Adding cells to fat grafts improves hair regrowth in early baldness, but effects lessen over time.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

Applying InlB321/15 to wounds sped up healing in mice.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

NAC1 controls certain enzymes that reduce root hair growth in Arabidopsis.

KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.

The HoxC gene cluster and its enhancers are essential for developing hair and nails in mammals.

The peach gene pCTG134 helps control the interaction between auxin and ethylene hormones during fruit ripening.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Certain drugs that block specific enzymes can help treat prostate diseases.

TAF4 is important for skin cell growth and helps prevent skin cancer in mice.

The AIRE gene variant rs2075876 is linked to a higher risk of alopecia areata in males.

Finasteride negatively affects fish reproduction and gonadal development.

Crossbreeding improves goat fiber quality, and specific genes affect hair traits and color.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Women with PCOS had higher SRAGE levels, possibly linked to BMI, not PCOS.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

PRP and HF-MSCs treatment improves hair growth, thickness, and density in androgenetic alopecia.

Finasteride effectively treats male pattern hair loss with a 1 mg daily dose.

The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Flutamide caused damage to male rat reproductive organs and may affect fertility.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.