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This review discusses the potential of plant-synthesized secondary metabolites as natural therapeutics for COVID-19 and reports no new clinical results.

This study analyzed social media posts and found discrepancies between patient-reported satisfaction and emotional responses to alopecia areata treatments, highlighting potential gaps between perceived and clinical efficacy.

This article reviews alopecia areata as a chronic autoimmune disease affecting hair follicles and discusses its association with other autoimmune conditions, but provides no new clinical findings.

This case report describes a patient with unrecognized systemic lupus erythematosus, who experienced myocarditis, polyneuropathy, and pericarditis, and recovered following cardiac support and medication.

A mixture of Dijon mustard, turmeric powder, and linseed oil can effectively treat alopecia barbae.

This study reported that CCT oligodeoxynucleotide induced patchy hair loss in male mice with specific genetic traits, suggesting gender and genetic preferences in immune response.

Lupus is a complex disease that requires personalized treatment because it varies greatly between individuals.

This study found that alkaloids isolated from Cucumis metuliferus fruit pulp demonstrated antiviral activity against IBDV in chicken embryo fibroblast cells and NDV in 10-day-old embryonated chicken eggs, while being non-cytotoxic.

This article discusses the historical and current uses of grape seeds in various industries but reports no new research findings.

In this cell study, seaweed extract from Hizkia fusiforme significantly increased the proliferation of dermal papilla cells, suggesting potential for promoting hair growth.

This study found that intramuscular anti-IFN-γ significantly stabilized and promoted hair regrowth in alopecia areata patients with patchy, progressive hair loss, whereas those with total baldness showed more limited improvement.

The study suggests that vaccination with soluble keratin peptides K71 and K31 significantly delayed the onset and progression of autoimmune alopecia areata in mice by inducing T cell anergy.

This study found that treatment with EGFR inhibitors or mitogen-activated kinase inhibitors may compromise the immune privilege of human scalp hair follicles, suggesting new directions for managing drug-induced folliculitis.

Follicular dystrophy in immunocompromised patients may be linked to medication or viral factors and can improve with treatment changes.

This study found that dysregulated microRNA expression in mice may be linked to aberrant gene activity that contributes to the development of alopecia areata.

This study observed that patients with recurrent furunculosis had different cytokine profiles compared to healthy subjects and that retinol stimulation altered cytokine secretion in both groups.

IL-10 may worsen alopecia areata instead of helping it.

In this study of C3H/HeJ mice, researchers observed that alopecia areata is associated with the expansion of exhausted-memory CD8 T cells in multiple organs, with autoreactive activation not fully explained by known mechanisms, shedding light on the immunological dynamics underlying the condition.

This review outlines the various adverse reactions to biologic therapies in Allergy/Immunology, emphasizing the clinical and management challenges due to overlapping reaction phenotypes and the need for more refined diagnostic and management strategies.

This study observed that individuals with Down syndrome exhibit early immune dysregulation, including multi-organ autoimmunity and hypercytokinemia, and found that the JAK inhibitor tofacitinib showed a good safety profile and reduced skin pathology in a Phase II trial.

This study found that multicomponent microarray patches for SARS-CoV-2 vaccination produced stronger immune responses and fewer side effects in mice compared to traditional intramuscular injection.

This study found that targeting IL-6, IL-1, and CCR6 signaling pathways may effectively reduce irradiation-induced alopecia and dermatitis in radiotherapy patients.

This study found that the MD-3 antibody significantly improved the survival of hair follicle allografts in nonhuman primates by reducing T-cell infiltration.

In this mouse study, the researchers found that the monoclonal antibody ME1 causes hair follicle inflammation by up-regulating TNFα, which can be reduced by TNFα and interleukin-1 inhibitors.

This article reviews current treatments for alopecia areata, discussing the potential role of JAK inhibitors and noting the need for further clinical trials, but it reports no new results.

This study found that patients receiving immune checkpoint inhibitors who have a history of psoriasis are at a higher risk for developing gastrointestinal and endocrine toxicities within one year compared to those without psoriasis.

This study found that systemic administration of NDP-MSH, a melanocortin receptor agonist, provided neuroprotective effects on dopaminergic nigrostriatal neurons in a mouse model of Parkinson's disease, reducing neuroinflammation and suggesting a role for regulatory T cells in these neuroprotective effects.

This study found that combining adipose-derived mesenchymal stromal cells with meglumine antimoniate reduced lesion size and parasite load in mice with leishmaniasis, suggesting potential for improved treatment.

In this study, researchers prepared a humanized CXCL12 antibody for alopecia areata treatment, finding it significantly delayed disease onset in mice and reduced immune cell activation, suggesting potential as an immune modulatory therapy.

This study demonstrated that the immunomodulatory drug FTY720 may enhance the survival of allogeneic fat grafts in mice by reducing immune rejection and improving neovascularization.