1 citations
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December 2013 in “Journal of Evolution of Medical and Dental Sciences” This historical review examines the diagnostic and etiological understanding of alopecia areata, emphasizing the evolution of theories and the impact of immunological data, while providing no new clinical results.
277 citations
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December 2019 in “Frontiers in Immunology” This review discusses the immunological basis and development of Janus kinase inhibitors for treating skin diseases and reports no new clinical findings.
January 2022 in “International Journal of Biology Pharmacy and Allied Sciences” This article discusses autoimmune diseases, detailing their types, symptoms, and potential management strategies, without providing new clinical findings.
December 2021 in “International Journal of Biology Pharmacy and Allied Sciences” This article discusses various autoimmune diseases, including their symptoms and management, and reports no new clinical findings.
November 2018 in “Journal of Investigative Dermatology” Lichen Planopilaris causes irreversible hair loss due to immune attacks on hair stem cells, but modulating PPAR-γ might help treat it.
This review discusses various treatment options for alopecia areata, focusing on manipulating the immune response around hair follicles, but reports no new clinical results.
2 citations
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January 2010 in “Case Reports in Medicine” This case report and literature review explore a potential immunological link between alopecia areata and relapsing polychondritis, suggesting that the latter might be a systemic manifestation of the former.
August 2024 in “Clinical and Medical Engineering Live” This literature review examines the complexities of childhood alopecia areata, focusing on its forms, gene expression, and causes, providing a comprehensive analysis of this autoimmune disorder.
4 citations
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November 2014 The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
35 citations
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August 2009 in “Journal of the American Academy of Dermatology” This study found a decreased number of follicular melanocytes in patients with alopecia areata, though it remains unclear if this decrease is due to autoimmune attack or rapid hair cycling.
169 citations
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February 2018 in “Immunity” In this study, researchers found that quiescent stem cells resist immune attack due to downregulated antigen presentation, which may help explain the immune evasion of early cancer-initiating cells.
17 citations
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January 1985 in “International Journal of Dermatology” In this study, minoxidil was found to suppress the activity of normal human T-lymphocytes in vitro, though the physiological relevance of this effect remains uncertain.
January 2024 in “International journal of homoeopathic sciences” This abstract discusses alopecia areata, highlighting its complex autoimmune pathogenesis involving immune cells and signaling molecules, and underscores the importance of accurate diagnosis and tailored management strategies, noting the need for further research to improve treatments.
This review examines complex regional pain syndrome (CRPS I) mechanisms, including immune dysregulation and psychological factors, but reports no new clinical results; the authors highlight potential diagnostic refinements.
17 citations
,
July 1994 in “Journal of Dermatological Science” This article reviews the genetic and potential environmental factors in alopecia areata's pathogenesis and suggests a polygenic model but reports no new clinical findings.
8 citations
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January 2008 in “European Journal of Pediatrics” This report describes two prepubertal children with autoimmune gastritis, highlighting the need to screen paediatric patients with organ-specific autoimmune diseases for co-existing conditions.
6 citations
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November 1988 in “Journal of the American Academy of Dermatology” The document concludes that hair analysis is not good for assessing nutrition but can detect long-term heavy metal exposure.
5 citations
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June 2022 in “Frontiers in immunology” This study observed that expanding regulatory T cells in the skin of mice with alopecia areata did not reverse the condition, indicating that additional immunotherapy may be necessary.
2 citations
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January 2020 in “American Journal of Clinical Research and Reviews” This study suggests that hair follicles may be the primary target in the onset of various skin diseases, potentially spreading to affect the surrounding epidermis.
1 citations
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May 2023 in “Prospects in Pharmaceutical Sciences” This study reviews current treatments for alopecia areata, highlighting that despite various options like corticosteroids and immunosuppressives, their limited efficacy and potential side effects are challenges, while targeting specific cytokines has shown promise except with TNF inhibitors, which may worsen the condition.
1 citations
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January 2017 in “Springer eBooks” This review discusses recent advances in understanding alopecia areata's disease mechanisms and highlights JAK molecules as promising therapeutic targets, but reports no new clinical results; controlled trials are needed.
1 citations
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September 2017 in “Journal of Pathology of Nepal” This study found that direct immunofluorescence of hair is a simple and non-invasive alternative for monitoring pemphigus vulgaris, matching skin biopsy results in the cases observed.
August 2023 in “Physician's journal of medicine” This review provides a detailed overview of Hashimoto thyroiditis, discussing its epidemiology, risk factors, genetic and environmental contributors, clinical presentations, diagnostic methods, and treatment options, emphasizing the importance of personalized treatment plans due to varied causes and symptoms.
December 2022 in “Rossijskij žurnal kožnyh i veneričeskih boleznej” This source highlights that the incidence of alopecia areata is increasing among children, and while corticosteroids and Janus kinase inhibitors show potential effectiveness and safety, they remain unapproved by the FDA for pediatric use.
January 2009 in “Springer eBooks” The document concludes that managing skin conditions during pregnancy is important and requires specialized care.
26 citations
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January 1994 in “Clinics in Dermatology” This article reviews advancements in burn care, emphasizing early wound excision's role in decreasing morbidity and mortality, but it reports no new clinical findings.
185 citations
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August 2005 in “Autoimmunity Reviews” This review discusses alopecia areata as a model for studying tissue-directed autoimmune diseases and reports no new clinical findings.
August 2025 in “Frontiers in Immunology” This case report is the first to document the coexistence of bullous pemphigoid, malignant tumors, and alopecia areata in a patient, highlighting the complete resolution of skin lesions with dupilumab and spontaneous hair regrowth without disease-specific treatment.
15 citations
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July 1999 in “Dermatologic Clinics” This article discusses the potential for targeted therapies in hair loss by exploring inflammatory and cytokine-mediated processes, but it presents no new clinical results.
1113 citations
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August 1999 in “The New England Journal of Medicine” This article discusses the biologic and psychosocial significance of hair, the current limitations in hair growth drugs, and anticipates future therapies based on advancing hair follicle research.