TLDR Relapsing polychondritis might be linked to alopecia areata due to immune system factors.
This document reported a third case of relapsing polychondritis following long-standing alopecia areata, suggesting a potential immunological link between the two conditions. The case involved a 71-year-old man with a 28-year history of alopecia universalis who developed relapsing polychondritis after a poison ivy incident. Treatment with corticosteroids led to the regrowth of his beard, although no other body hair regrew. The study proposed that the immune response targeting chondroitin sulfate in hair follicles might extend to cartilage, contributing to relapsing polychondritis. The findings highlighted the complex immune interactions in alopecia areata and its potential systemic manifestations.
391 citations
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January 2010 in “Journal of The American Academy of Dermatology” Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.
38 citations
,
July 2009 in “Current opinion in pediatrics, with evaluated MEDLINE/Current opinion in pediatrics” Alopecia areata is a common autoimmune disease affecting hair follicles, with unclear causes and a need for better treatments.
148 citations
,
September 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia areata is an autoimmune disorder causing hair loss, linked to specific hair follicle antigens and genetic factors.
13 citations
,
July 2003 in “Annals of the Rheumatic Diseases” Co-trimoxazole successfully treated a girl with multiple autoimmune symptoms.
30 citations
,
December 2001 in “Experimental dermatology” Gonadal hormones significantly affect the severity of alopecia areata in mice.
April 2019 in “International journal of research in dermatology” A child with rough nails also had hair loss and allergies.
