Alopecia Areata And Relapsing Polychondritis Or Mosaic Autoimmunity? The First Experience Of Co-Trimoxazole Treatment
July 2003
in “
Annals of the Rheumatic Diseases
”
New to Alopecia Areata? There is a guide in the encyclopedia. Read the guide → Studysummary This case report describes a 13-year-old girl with various autoimmune symptoms successfully treated with the antibiotic and immunomodulatory drug co-trimoxazole; its potential role in autoimmune disease treatment is explored. Our plain-language summary of this paper — not a Tressless recommendation.
The document discussed a case of alopecia areata and relapsing polychondritis treated with co-trimoxazole. Initially, the patient received intravenous augmentin (1 g every 8 hours) for 5 days, which resulted in sustained diffuse oedema and erythema of the auricle, sparing the ear lobe. Upon switching to a combined treatment of prednisone (40 mg/day) and co-trimoxazole (50 mg/kg/day), there was a marked reduction in oedema and erythema within 2 days. This case suggested that co-trimoxazole might be effective in treating these conditions.
