Clinical And Histopathological Findings In Patients With Follicular Dermatoses: All Skin Diseases Start In The Hair Follicles As A New Hypothesis

January 2020 in “ American Journal of Clinical Research and Reviews ”

Department of Dermatology, College of Medicine, University of Baghdad. Iraqi and Arab Board for Dermatology and Venereology, Baghdad Teaching Hospital, Medical City, Baghdad, Iraq. Center of Dermatology, Baghdad Teaching Hospital, Medical city, Baghdad, Iraq.

follicular dermatoses hair follicles perifollicular lymphocytes follicular invasion histopathological evaluations epidermis etiopathogenesis skin disorders

TLDR All skin diseases might start in hair follicles.

The study conducted at Baghdad Teaching Hospital involved 60 patients with follicular dermatoses, revealing that all skin diseases might originate in hair follicles before spreading to the epidermis. Histopathological evaluations of biopsies from 40 patients showed perifollicular lymphocytes, follicular invasion, degeneration, and other changes, supporting the hypothesis that hair follicles are the primary target in the etiopathogenesis of skin disorders. The study suggested that the anatomical and immunological characteristics of hair follicles make them susceptible to early pathological processes, potentially leading to broader skin involvement.

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