127 citations
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January 2000 in “Journal of Investigative Dermatology” This study found that pro-inflammatory cytokines and apoptotic mechanisms, specifically involving granzyme B and Fas pathways, are associated with chronic alopecia areata, indicating their potential role in the disease's persistence.
This study found that activating KATP channels with pinacidil may reduce antioxidant levels and mortality in honey bees, suggesting a role in regulating antiviral immunity through reactive oxygen species.
24 citations
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August 2022 in “Immunity” This study found that control of Demodex mite colonization in mice required skin ILC2s and IL-13, highlighting their role in maintaining HF integrity and limiting mite overgrowth.
November 2022 in “JAAD case reports” This report diagnosed a 68-year-old man with comedonal folliculotropic mycosis fungoides based on clinical and histopathological findings, and found pegylated interferon alpha-2a with isotretinoin beneficial in reducing skin lesions.
14 citations
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April 2017 in “American Journal of Transplantation” This review examines nonmalignant skin toxicities from immunosuppressive and transplant-related medications, emphasizing the need for effective identification and management by care providers; it presents no new research findings.
8 citations
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January 2013 in “Australasian journal of dermatology” This review examines trichodysplasia spinulosa, a rare virus-linked skin condition in immunosuppressed individuals, noting its clinical features and highlighting antiviral treatment efficacy, without new clinical results.
36 citations
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May 2020 in “Journal of the European Academy of Dermatology and Venereology” Dermatologists should watch for skin symptoms in COVID-19 patients, prioritize urgent cases, and use telemedicine.
6 citations
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July 2021 in “Bulletin of the National Research Centre/Bulletin of the National Research Center” This review discusses the transmission and immune response of SARS-CoV-2 and highlights ongoing research for developing vaccines and antiviral treatments, but it presents no new clinical findings.
86 citations
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June 2018 in “Cochrane library” This review update suggests that mycophenolate mofetil may increase complete disease remission in proliferative lupus nephritis compared to intravenous cyclophosphamide, but with low certainty of evidence.
December 2021 in “Zenodo (CERN European Organization for Nuclear Research)” This case report describes a post-COVID syndrome patient who experienced symptoms like headache, joint pain, and swollen lymph nodes; treatment with Erbisol drugs reportedly alleviated symptoms and normalized immunological parameters.
9 citations
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April 2021 in “Frontiers in Immunology” This review discusses the role and mechanisms of unconventional lymphocytes in promoting tissue repair and maintaining mucosal barrier integrity in the skin, gut, and lungs, but reports no new findings.
January 2022 in “International Journal of Biology Pharmacy and Allied Sciences” This article discusses autoimmune diseases, detailing their types, symptoms, and potential management strategies, without providing new clinical findings.
18 citations
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January 2021 in “Theranostics” This study found that actively targeted AN2728-loaded nanocarriers reduced inflammation and improved skin condition in a mouse model of psoriasiform inflammation compared to free drug and non-targeted nanoparticles.
18 citations
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January 2016 in “Journal of Clinical Medicine Research” This case report describes a patient with SLE who developed acute inflammatory demyelinating polyneuropathy, experiencing significant improvement after treatment with intravenous immunoglobulin, methylprednisolone, and cyclophosphamide.
This study investigated dual TCR Treg cells in mouse tissues, revealing a high proportion and diverse pairing patterns compared to single TCR Tregs, providing insights into their origins and characteristics across different tissue locations.
August 2023 in “Dermatology and Therapy” This review discusses the increasing reports of rare cutaneous side effects from topical imiquimod, aiming to inform physicians and dermatologists about its potential adverse effects as its use expands.
610 citations
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April 2014 in “Nature Reviews Immunology” This review discusses the complex mechanisms regulating skin immunity to balance host defense with inflammation, but reports no new findings.
15 citations
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January 2022 in “Immune Network/Immune network” This review summarizes the pathophysiology and immune mechanisms of inflammatory skin diseases like psoriasis and atopic dermatitis, highlighting the therapeutic potential of targeted immunotherapies, but reports no new clinical results.
3 citations
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September 2023 in “Frontiers in immunology” This study discusses the epithelial-immune microenvironment in chronic skin diseases, such as psoriasis and atopic dermatitis, and highlights current and future treatment strategies targeting inflammatory loops within these diseases.
In this clinical case study, a 30-year-old man with systemic lupus erythematosus was diagnosed with both catastrophic antiphospholipid syndrome and acquired haemophilia A, successfully treated with immunosuppressive therapy, plasma exchange, and IVIG, leading to a favourable outcome.
September 2024 in “Annals of Dermatology” This study established an IRGDS model with diagnostic capability for alopecia areata, which may serve as an auxiliary marker for the condition.
41 citations
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July 2019 in “Clinical Cosmetic and Investigational Dermatology” This paper explores the complex immune processes and cellular diversity that enable the skin to heal and resist invasion, and highlights its potential as a model for studying regeneration.
1 citations
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October 2024 in “Journal of Clinical Immunology” This study observed that adult Netherton syndrome patients showed a range of normal to diminished immune responses to polysaccharide, conjugate, and mRNA-based vaccines, with responses generally overlapping those of healthy controls, suggesting no consistent B- or T-cell immunodeficiency in this population.
August 2022 in “Brain and Development” In this case report, a nine-year-old girl with both chronic inflammatory demyelinating polyneuropathy and alopecia universalis showed improvement in muscle weakness and hair loss after treatment with intravenous immunoglobulin and corticosteroids.
105 citations
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December 2017 in “Journal of Biological Engineering” This review discusses the challenges of skin graft acceptance and examines current strategies and alternatives for full-thickness skin replacement and repair, noting that immunological rejection remains a significant hurdle.
1 citations
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January 2024 in “Dermatologic Therapy” This study found that combining excimer light at 308 nm with tacrolimus 0.1% was more effective in treating alopecia areata of the scalp compared to excimer light alone, as indicated by a greater reduction in the SALT score and better improvement in Treg function.
4 citations
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May 2023 in “Composites Part B: Engineering” In this study, a novel nanocomposite hydrogel was developed for diabetic wound care, demonstrating superior tissue adhesion, antibacterial properties, and healing capabilities in vivo and in vitro, while also allowing real-time pH monitoring to aid clinical management.
May 2024 in “Frontiers in Medicine” Targeted immunological therapies offer safer and more effective treatments for skin conditions like eczema and psoriasis.
June 2023 in “Institutional Repositories DataBase (IRDB)” In this study, researchers observed six patterns of skin reactions in COVID-19 patients and noted potential skin responses following vaccination, although the mechanisms remain unclear.
3 citations
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September 2023 in “Journal of Photochemistry and Photobiology A Chemistry”