A First Case of Childhood Chronic Inflammatory Demyelinating Polyneuropathy Associated with Alopecia Universalis
November 2022
in “
Brain and Development
”
TLDR A nine-year-old girl with muscle weakness and total hair loss improved with specific treatments.
This document reports the first case of a nine-year-old Japanese girl with childhood chronic inflammatory demyelinating polyneuropathy (CIDP) associated with alopecia universalis (AU). The girl developed alopecia at age 2, progressive muscle weakness at age 4, and loss of walking ability at age 7. She was successfully treated with a combination of intravenous immunoglobulin (IVIg) and corticosteroids, which improved both her muscle weakness and alopecia. The presence of serum IgG-GM2 type anti-glycolipid antibodies may be linked to this rare combination of diseases.
