TLDR Immunological treatment improved both neuropathy and alopecia.
A 42-year-old male experienced whole body alopecia and limb weakness, initially unresponsive to prednisolone. Diagnosed with multifocal acquired demyelinating sensory and motor neuropathy in 2011, he was treated with intravenous immunoglobulin (IVIg), which improved muscle strength. After three years, he experienced remitting limb weakness and received IVIg again, resulting in improvement of both alopecia and limb weakness. This case suggested an immunological pathomechanism linking the neuropathy and alopecia, as both conditions improved with immunomodulatory treatment.
122 citations
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November 1984 in “Journal of the American Academy of Dermatology” No single treatment is consistently effective for alopecia areata, and more research is needed.
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May 2021 in “Neuropathology & applied neurobiology/Neuropathology and applied neurobiology” Correct diagnosis and treatment are crucial for effective management of lipid storage myopathies.
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April 2017 in “Journal of Dermatology and Dermatologic Surgery” IVIG therapy was linked to hair regrowth in two patients with hair loss, but it's not recommended due to its risks and costs.
January 2025 in “Frontiers in Immunology” IVIG therapy significantly improved symptoms in a patient with APS-2 and SPS.
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