A Case of Multifocal Acquired Demyelinating Sensory and Motor Neuropathy with Whole Body Alopecia
January 2014
in “
Rinsho Shinkeigaku
”
Studysummary This case report suggests an immunological link between multifocal acquired demyelinating sensory and motor neuropathy and alopecia, with both conditions improving after treatment with intravenous immunoglobulin. Our plain-language summary of this paper — not a Tressless recommendation.
A 42-year-old male experienced whole body alopecia and limb weakness, initially unresponsive to prednisolone. Diagnosed with multifocal acquired demyelinating sensory and motor neuropathy in 2011, he was treated with intravenous immunoglobulin (IVIg), which improved muscle strength. After three years, he experienced remitting limb weakness and received IVIg again, resulting in improvement of both alopecia and limb weakness. This case suggested an immunological pathomechanism linking the neuropathy and alopecia, as both conditions improved with immunomodulatory treatment.