Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, researchers identified 19 genetic risk loci and highlighted 16 candidate causal genes, including immune-related ones, associated with polycystic ovary syndrome, emphasizing the role of specific immune cells like T cells and NK cells in its pathogenesis.

This review explores advancements in bioprinting technologies for developing in vitro skin models that replicate immune-mediated skin diseases, highlighting their potential to reduce animal testing and enhance research and product testing capabilities in dermatology.

This review discusses zinc supplementation as a complementary therapy for chronic hepatitis C, noting its potential benefits in improving treatment outcomes and reducing side effects, but reports no new clinical results.

This review discusses the classification, diagnosis, and potential treatment pathways for Alopecia Areata, emphasizing the complex genetic and immunological factors involved, but reports no new clinical results.

This narrative review proposes the concept of "repigmentation competence" for vitiligo lesions, suggesting that therapy responses are influenced by lesion-specific biological factors related to immune, regenerative, regulatory, and microenvironmental processes, and highlights the emerging role of combination therapies targeting these pathways.

This study found that allergic rhinitis is linked to a higher risk of developing androgenetic alopecia, while second-generation H1-antihistamine use was associated with a reduced risk, especially in younger patients.

In this study, researchers conducted a large genome-wide association meta-analysis and found 30 significant genetic loci linked to the risk of dermatophytosis, shedding light on the roles of keratin biology, skin barrier defects, immune dysfunction, and obesity in the disease.

This review discusses the role of immune cells in the pathogenesis of alopecia areata and highlights emerging immunomodulatory strategies and novel therapeutic targets aimed at offering more effective and durable treatments for this autoimmune hair loss disorder.

This study suggests that using cell-free dexamethasone-primed stem cell media may offer a promising alternative treatment for systemic lupus erythematosus, showing immunomodulatory benefits and therapeutic efficacy in reducing various complications.

This study developed a mathematical model to simulate immune interactions and hair cycle dynamics in alopecia areata, identifying influential factors affecting hair growth and offering insights into potential treatment strategies by targeting immune dysregulation.

In this study, researchers developed a mathematical model to explore how immune system dynamics affect hair follicle behavior in alopecia areata, identifying key parameters influencing disease progression and suggesting potential treatment strategies targeting immune dysregulation.

This study developed a mathematical model to explore the interactions between hair cycle dynamics and immune system activity in alopecia areata, providing insights into disease progression and potential targets for treatment by simulating immune response effects on hair follicles.

This review discusses strategies to enhance mesenchymal stem cell therapy effectiveness but reports no new clinical results; it highlights the need for improved consistency and efficacy in MSC-based treatments.

This review discusses how inflammation influences hair follicle stem cell activities like wound healing and follicle cycling and suggests a potential link between inflammation, stem cell activation, and programmed cell death.

This review discusses sex differences in immune responses to COVID-19 and highlights that males tend to experience more severe symptoms and higher mortality but reports no new clinical findings.

This review discusses the current and emerging methods for profiling skin microbes to advance our understanding of the microbiome in skin disease, but it reports no new clinical findings.

This study investigated the molecular mechanisms behind cashmere goat coat types by analyzing gene expression during hair follicle development stages, identifying regulatory pathways involved in metabolism, immune response, and the quiescent state of follicles, potentially aiding in genetic selection for improved cashmere production.

This review highlights recent advancements in understanding and treating alopecia, emphasizing genetic and immune factors involved in different forms, and discusses emerging therapies such as gene-editing and exosome-based treatments, though achieving complete hair regrowth remains a challenge.

This review of studies published after 2020 found that probiotics may significantly reduce acne lesions and improve skin health in individuals with acne vulgaris, though further high-quality research is needed for confirmation and treatment optimization.

In this study, researchers found that a cold atmospheric plasma-activated hydrogel containing interleukin-2 significantly enhanced hair regeneration in a depilated mouse model, promoting larger hair follicles and faster hair growth phase transition, suggesting it as a potential treatment for hair loss.

This review explored the relationship between alopecia areata and gut microbiota imbalances, noting potential immune dysregulation due to microbiome alterations. It highlighted promising results from fecal microbiota transplantation in treating alopecia universalis, indicating a need for further research into microbiome-targeted therapies.

This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.

This article reviews the clinical presentation and histopathologic features of alopecia areata and proposes a hypothesis for its development, but it reports no new clinical results.

This review discusses the mechanisms and potential therapeutic benefits of mesenchymal stromal cell-derived extracellular vesicles delivered via biomaterials, but reports no new clinical results.

Mammalian organs regenerate using stem cells and cell plasticity, but this ability declines with age.

This review discusses recent advances in understanding gender differences in skin and their implications for dermatologic diseases, but it reports no new experimental results; ongoing research is necessary for translating these insights into clinical practice.

This review discusses recent findings on the plasticity and regulation of epithelial stem cells and reports no new experimental results.

This review discusses the extraction, purification, modification, and biological activity of polysaccharides from Traditional Chinese Medicine and reports no new research findings.

This review discusses the functions and potential therapeutic targeting of TRP ion channels in the skin, noting their involvement in both physiological processes and various pathological conditions, but reports no new experimental results.

This study identified significant genetic associations with frontal fibrosing alopecia at four genomic loci, suggesting it is a genetically predisposed immuno-inflammatory disorder influenced by the HLA-B*07: 02 allele.