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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Burn scars form abnormally due to changes in wound healing, and more research is needed to improve treatments.

Skin healing from blisters can delay hair growth as stem cells focus on repairing skin over developing hair.

Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.

Wound healing is complex and requires more research to enhance treatment methods.

Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.

Skin aging reflects overall body aging and can indicate internal health conditions.

FOXN1 is crucial for thymus development and immune response in Xenopus laevis.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Fat cells in the skin help start healing and form important repair cells after injury.

Aging slows wound healing due to weaker cells and immune response.

Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.

Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.

Stress hormones like cortisol may trigger psoriasis flare-ups.

Conditioned media from human amniotic fluid-derived stem cells helps skin heal and protects against aging from sun exposure.

Implanting hair-follicle stem cells in mice brains helped repair brain bleeding and reduced brain inflammation.

Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.

The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.

Manipulating cell cleanup processes could help treat hair loss.

Recent findings suggest that genetic factors, immune system issues, and skin cell defects might contribute to the development of hidradenitis suppurativa.

Certain immune-related proteins are higher in people with alopecia and their healthy relatives, hinting at a genetic link.

Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.

Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Coffee bean residue extract helps hair growth by activating cell processes.

Denosumab, a bone loss treatment, may cause hair loss and skin reactions due to immune system effects.

The reviewers found the manuscript on inflammation's role in cancer stem cells to be relevant but suggested it needs clarity, more background information, discussion on immune cells' role in tumors, updated references, and grammar corrections.

The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.

Reviewers suggest clarifying the abstract, adding background on inflammation's effect on cancer, discussing immune cell roles, including counter studies, and correcting grammar.