January 2026 in “IECCMEXICO” This review highlights how chronic inflammatory skin disorders like psoriasis and atopic dermatitis may be better understood as manifestations of systemic immune dysregulation rather than just skin issues, suggesting that recognizing these conditions as markers of broader immune imbalance can improve diagnosis and medical education.
3 citations
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April 2025 in “Journal of Feline Medicine and Surgery” In this review, the authors examined the clinical presentations, differential diagnoses, and management strategies for feline immune-mediated skin diseases, focusing on conditions like pemphigus complex and cutaneous lupus erythematosus, highlighting that despite their rarity, these diseases can lead to severe systemic issues in cats.
December 2025 in “Journal of Investigative Dermatology” Immune system issues may contribute to female pattern hair loss.
January 2021 in “Middle East journal of applied sciences” This article discusses the widespread issue of zinc deficiency affecting plant, animal, and human health, and reports no new clinical results; the authors emphasize the need for adequate zinc availability in agriculture and nutrition.
January 2024 in “International Journal of Homoeopathic Sciences” This abstract outlines the issue of hair loss caused by various factors, including stress and autoimmune disorders like alopecia areata, which results in spot baldness, but does not provide specific study results.
7 citations
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November 2018 in “British Journal of Dermatology” Alopecia areata is caused by immune system issues, and JAK inhibitors might help treat it.
November 2023 in “Journal of Investigative Dermatology” EGFR-targeted cancer therapy can cause skin issues starting at hair follicles, leading to inflammation.
4 citations
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April 2004 in “Medical veritas” This journal serves as a platform for diverse perspectives on vaccine-related issues, but the abstract itself reports no new scientific findings.
February 2024 in “Recima21” This study explored the connections between Covid-19 and hair loss issues like telogen effluvium and alopecia areata, highlighting the virus's potential trigger effect and underscoring the importance of comprehensive post-Covid-19 treatment strategies that consider immune, psychological, and hair cycle factors.
June 2023 in “Zenodo (CERN European Organization for Nuclear Research)” In this abstract, the issue of "microinflammation" in hair follicles, central to androgenetic alopecia, is described as involving an inflammatory process with Langerhans cells and keratinocytes presenting antigens to T lymphocytes, leading to an immune response with macrophages or natural killer cells destroying these antigens.
August 2025 in “Quality in Sport” In this review, the authors highlighted the importance of vitamin A for vision, immune function, growth, and skin, noting that deficiency can lead to serious health issues like night blindness and increased infection risk, while excessive intake poses toxicity risks, particularly from supplements.
22 citations
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March 1994 in “Journal of Heredity” In this study, researchers identified a mutation in mice that causes hair loss and immune system issues, located on chromosome 18.
7 citations
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June 2024 in “Communications Medicine” In this study, researchers analyzed spaceflight data from various sources and found that skin issues during spaceflight are linked to DNA damage, mitochondrial dysregulation, and gene alterations, while also highlighting the skin's adaptability post-flight.
January 2024 in “International journal of advanced biochemistry research” In this study, eight dogs with severe itching and skin issues caused by Demodex canis mites showed partial improvement after one month and full recovery in two months following treatment with fluralaner, antibiotics, immune boosters, and omega supplements.
April 2023 in “Journal of Investigative Dermatology” Staphylococcus epidermidis affects hair growth and metabolism, suggesting it could help manage hair growth issues.
16 citations
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June 2025 in “Journal of Composites Science” This study investigated chitosan–hydroxyapatite biocomposites, finding them to enhance anti-inflammatory cytokine expression, support cellular activities, and reduce pro-inflammatory cytokines in a dermatitis model, while highlighting gaps in understanding their immune modulation and issues with reproducibility for clinical use.
5 citations
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February 2022 in “Seminars in cell & developmental biology” This review discusses the complexities of hidradenitis suppurativa pathogenesis, highlighting issues with Notch signaling, immune dysregulation, and the role of keratinocytes and ECM, but reports no new clinical results.
1 citations
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April 2016 in “Journal of The American Academy of Dermatology” A man developed a rare skin condition and drug-induced lupus, highlighting the need for biopsy in diagnosing skin issues caused by sunlight.
June 2026 in “Frontiers in Cell and Developmental Biology” This review outlines recent advancements in understanding how micro-RNAs (miRNAs) influence hair regeneration, highlighting their role in stimulating hair growth and potential therapeutic approaches, while also addressing the challenges of clinical translation due to miRNAs' complex roles and delivery issues.
This study used a mouse model to reveal that S100A4-positive cells, specifically fibroblasts and immune cells, play a crucial role in nipple development, essential for successful lactation, despite no issues with mammary morphology or milk production.
January 2026 in “Inflammation and Regeneration” This review highlights that two-photon excitation microscopy is a valuable tool for visualizing live skin structures and immune responses at high resolution, though its clinical use is hindered by safety and cost issues.
December 2024 in “International Journal of Health Sciences and Research” This study describes the case of a 22-year-old female with alopecia areata linked to vitamin D deficiency, highlighting the importance of early diagnosis and management of deficiency to prevent broader health issues.
40 citations
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January 2022 in “Nutrients” This review explores the potential impact of nutrition on immune-mediated inflammatory skin diseases and evaluates whether dietary changes could help in treatment planning, but it presents no new clinical outcomes.
June 2026 in “Frontiers in Bioengineering and Biotechnology” This review outlines the transition from simple hair follicle organoids to immune-competent microphysiological systems, addressing limitations in replicating native hair follicle immune features and discussing their applications in disease modeling and regenerative medicine.
April 2026 in “International Journal of Clinical Oncology” This review found that adding immune checkpoint inhibitors to cancer treatment regimens likely increases the incidence of specific drug-related skin toxicities in adult Asian patients, highlighting the need for careful monitoring and management strategies.
This research highlighted varying findings on the use of daily emollients for preventing atopic dermatitis in infants, with one study noting a reduction in incidence, while another found no preventive effect.
September 2020 in “British Journal of Dermatology” This article provides issue information for the September 2020 edition of the British Journal of Dermatology and contains no new research findings.
November 2018 in “The Journal of Allergy and Clinical Immunology: In Practice” This report documents the successful use of theophylline in treating an 11-year-old girl with a rare immunodeficiency syndrome, suggesting potential in drug repurposing for primary immunodeficiency disorders and asthma.
11 citations
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October 2023 in “ACS Pharmacology & Translational Science” This review discusses the potential of plant-derived natural compounds with immunomodulatory properties as novel antiviral therapies, highlighting their possible mechanisms against various viral infections in the context of traditional and biotechnological applications.
This article reviews the nutritional needs and challenges for the elderly, emphasizing the benefits of antioxidants and healthy fats for immune support and overall health, but presents no new clinical results.