Issue Information: Studies on Allergic and Inflammatory Skin Diseases

    March 2023 in “ Allergy ”
    H Brough, S Sindher, K Nadeau, P Gevaert, J De Craemer, C Bachert, M Blauwblomme, A Chaker, C Cingi, P Hellings, C Hopkins, V Hox, W Fokkens, L Klimek, V Lund, R Msges, J Mullol, O Pfaar, G Scadding, P Tomazic, T Van Zele, S Vlaminck, M Wagenmann, S Toppila-Salmi, I Alobid, D Tan, C Lodge, E Walters, A Lowe, D Bui, G Bowatte, R Kandane-Rathnayake, F Aldakheel, B Erbas, G Hamilton, P Thomas, M Hew, M Tang, M Abramson, J Perret, S Dharmage, B Sousa-Pinto, H Schnemann, A S-Sousa, R Vieira, R Amaral, J Anto, W Czarlewski, A Bedbrook, L Brussino, V Kvedariene, D Larenas-Linnemann, Y Okamoto, M Ventura, I Agache, I Ansotegui, K Bergmann, S Bosnic-Anticevich, G Canonica, V Cardona, P Carreiro-Martins, T Casale, L Cecchi, T Chivato, D Chu, E Costa, A Cruz, S Giacco, P Devillier, P Eklund, B Gemicioglu, T Haahtela, J Ivancevich, Z Ispayeva, M Jutel, P Kuna, I Kaidashev, M Khaitov, H Kraxner, D Laune, B Lipworth, R Louis, M Makris, R Monti, M Morais-Almeida, M Niedoszytko, N Papadopoulos, V Patella, N Pham-Thi, F Regateiro, S Reitsma, P Rouadi, B Samolinski, A Sheikh, M Sova, A Todo-Bom, L Taborda-Barata, J Sastre, I Tsiligianni, A Valiulis
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    Studysummary This research highlighted varying findings on the use of daily emollients for preventing atopic dermatitis in infants, with one study noting a reduction in incidence, while another found no preventive effect.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The document discussed various studies related to allergic and inflammatory skin diseases, particularly atopic dermatitis. It highlighted the role of the skin as an immune organ and the impact of environmental factors on skin barrier integrity. Brough et al. discussed the short-term use of emollients for preventing atopic dermatitis in high-risk infants, while Chaoimh and Lad et al. found that daily emollient use from the first week of life until two months reduced atopic dermatitis incidence in the first year. Conversely, Bradshaw et al. found no benefit of emollients in preventing atopic dermatitis or other allergies. Jeong et al. identified the importance of Rab-25 in epidermal differentiation and its deficiency's correlation with atopic dermatitis severity. Renert-Yuval, Pavel, and Del Duca et al. explored the effects of Th2 modulation with dupilumab on immune and hair keratin dysregulation in alopecia areata, especially in patients with an atopic background.
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