research Expanding The Phenotype Of Hyper-IgE Syndrome: Heterozygous Variant In IL6ST With Elevated Serum IgE And Isolated Abscesses
A new IL6ST gene variant may cause a unique form of hyper-IgE syndrome with skin abscesses and high IgE levels.
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research Crosstalk Between Endothelial Cells and Dermal Papilla Entails Hair Regeneration and Angiogenesis During Aging
Communication between blood vessel and hair follicle cells decreases with age, affecting hair growth and blood vessel formation.
research Pharmacologic Inhibition of JAK-STAT Signaling Promotes Hair Growth
Blocking JAK-STAT signaling can lead to hair growth.
research Peripheral Blood Gene Expression in Alopecia Areata Reveals Molecular Pathways Distinguishing Heritability, Disease, and Severity
Blood tests can help understand the genetic differences in people with alopecia areata, including how severe it is and if it's inherited.
research Single-Cell Transcriptomics Reveals Lineage Trajectory of Human Scalp Hair Follicle and Informs Mechanisms of Hair Graying
The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.
research A Guide for Building Biological Pathways with Two Case Studies: Hair and Breast Development
The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
research Fibroblast Heterogeneity and Functions: Insights from Single-Cell Sequencing in Wound Healing, Breast Cancer, Ovarian Cancer, and Melanoma
Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.
research Generating Detailed Intercellular Communication Patterns in Psoriasis at the Single-Cell Level Using Social Networking, Pattern Recognition, and Manifold Learning Methods to Optimize Treatment Strategies
New insights into cell communication in psoriasis suggest innovative drug treatments.
research TNC+ Fibroblasts Involved in Skin Inflammation via Neuro-Immune Interactions with T Cells
TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.
research Hedgehog Signaling Reprograms Hair Follicle Niche Fibroblasts to a Hyper-Activated State
Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.
research A Hairy Situation: PADIs in Regeneration and Alopecia
Enzymes called PADIs play a key role in hair growth and loss.
research Hydrogel Crosslinking Modulates Macrophages, Fibroblasts, And Their Communication During Wound Healing
Softer hydrogels help wounds heal better with less scarring.
research Interleukin-6 Null Mice Paradoxically Display Increased STAT3 Activity and Wound-Induced Hair Neogenesis
Mice without the IL-6 gene had more hair growth after injury due to higher activity of a related protein, Stat3.
research A New Combination Therapy for Scalp Alopecia Areata: An Approach to High Negative Pressure Microdermabrasion with Intralesional Steroids
The combination therapy of microdermabrasion and steroid injections is more effective for treating scalp Alopecia Areata than steroid injections alone.
research A New Combination Therapy for Scalp Alopecia Areata: A Study of High Negative Pressure Microdermabrasion and Intralesional Steroids
Combining microdermabrasion with steroid injections improves hair regrowth in scalp alopecia areata.
research Comparative Study of the Efficacy of Treatments for Androgenetic Alopecia Using Intradermal Therapy: Minoxidil and Finasteride
Minoxidil slightly increased hair volume more than Finasterida, but both reduced hair loss similarly.
research Editorial Comments on Hair Loss After Ileal Pouch-Anal Anastomosis
Some patients experience temporary hair loss after ulcerative colitis surgery, likely due to illness rather than the surgery itself, and it usually grows back within six months.
research Historical Aspects of Dermatomycoses
Doctors have known about fungal skin infections for a long time, but only made major progress in understanding and treating them since the mid-1800s.
research Interventions for Central Serous Chorioretinopathy: A Network Meta-Analysis
The study aims to find the best treatment for central serous chorioretinopathy by comparing various options.
research Current Technique of Follicular Unit Hair Transplantation
Follicular unit hair transplantation is the standard method for natural-looking hair restoration in androgenic alopecia.
research Validation of a Spanish-Language Adaptation of the Hair Specific Skindex-29 Scale
The Spanish version of the Hair Specific Skindex-29 scale is a reliable and valid way to measure the impact of hair loss on women's quality of life.
research Anagen Hair Follicles Transplanted Into Mature Human Scars Remodel Fibrotic Tissue
Transplanting growing hair follicles into scars can help regenerate and improve scar tissue.
research Ammonium Bisulfite Contact Dermatitis: Face Eczema Due to a Bleaching Ointment Used During Hair-Dyeing
Ammonium bisulfite in hair bleach can cause facial eczema.
research Alopecia After Ileal Pouch-Anal Anastomosis
Some patients temporarily lost hair after a certain bowel surgery, but it grew back without needing special treatment.
research Low-Level Laser Therapy in Wound Healing
Low-Level Laser Therapy helps heal wounds and regenerate tissue when used correctly.
research Adrenal Cortex Tumors and Hyperplasias
Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.
research Epidemiologic and Molecular Characterization of Zoonotic Dermatophytes from Pet Dogs and Cats in Egypt
Pets in Egypt can pass skin fungus, especially Microsporum canis, to humans, with outdoor and young pets being more at risk.
research Characterization And Neural Differentiation In Vitro Of Stem Cells From Human Deciduous Tooth Pulp
Dental pulp stem cells might not reliably become neurons.
research Aurora Guerra-Tapia: Female Alopecia
Early diagnosis and treatment are crucial for managing female hair loss effectively.