research Modeling Cell-Cell Communication for Immune Systems Across Space and Time
The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.
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research Medical Treatment of Hepatocellular Carcinoma: Any Progress?
As of 1994, treatments for liver cancer had not significantly improved patient survival.
research ACTH as First Line Treatment for Acute Calcium Pyrophosphate Crystal Arthritis in 14 Hospitalized Patients
ACTH may be an effective first-line treatment for acute calcium pyrophosphate crystal arthritis.
research Prevention of Alopecia in Medical and Interventional Chemotherapy Patients
Cold caps and certain drugs may help prevent or reduce hair loss from chemotherapy, but more research is needed.
research Successful Treatment of Palmoplantar Pustular Psoriasis with Brodalumab
Brodalumab effectively treated a man's severe hand and foot psoriasis.
research Hair-Cycle Changes in Two Patients Taking Tocilizumab
Tocilizumab treatment was associated with significant hair regrowth in one patient and temporary hair loss followed by regrowth in another.
research Impaired Responses of Peripheral Blood Mononuclear Cells to T-Cell Stimulants in Alopecia Areata Patients with a Poor Response to Topical Immunotherapy
Poor response to topical immunotherapy in alopecia areata patients is linked to impaired cell responses.
research Lokivetmab Improved Pruritus in a Dog With Cutaneous Epitheliotropic Lymphoma
Lokivetmab reduced itching in a dog with skin lymphoma.
research The Role of Platelet-Rich Plasma in the Prevention of Chemotherapy-Induced Alopecia
Platelet-rich plasma doesn't prevent hair loss from chemotherapy, and mononuclear cells only help against hair loss from one specific chemotherapy drug.
research Immune-Mediated Skin Reactions Induced by Recombinant Antibodies and Other TNF-Alpha Inhibitors
TNF-alpha inhibitors can cause various immune-related skin issues.
research Improvement of Recalcitrant Dissecting Cellulitis of the Scalp After a Trial of Upadacitinib
Upadacitinib significantly improved a man's severe scalp condition when other treatments failed.
research Mutation-Specific siRNA Knockdown of GJB2: Potential Gene Therapy for Keratitis-Ichthyosis-Deafness Syndrome
Targeted siRNA therapy may be a promising treatment for KID syndrome by reducing mutant gene expression and improving cell communication.
research COVID-19 and Sex Differences: Mechanisms and Biomarkers
Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.
research Tregs: Where We Are and What Comes Next?
The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
research Probiotic Bacteria Induce a Glow of Health
Probiotic bacteria improved skin and hair health in aged mice.
research Regulatory T Cells: The Many Faces of Foxp3
Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.
research The Changing Landscape of Alopecia Areata: The Therapeutic Paradigm
New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.
research Acne as a Chronic Systemic Disease
Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.
research Ovarian Leukocyte Distribution and Cytokine/Chemokine mRNA Expression in Follicular Fluid Cells in Women with Polycystic Ovary Syndrome
Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
research Proinflammatory Cytokines Regulate Epidermal Stem Cells in Wound Epithelialization
Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
research Alopecia Areata Is Characterized by Dysregulation in Systemic Type 17 and Type 2 Cytokines, Which May Contribute to Disease-Associated Psychological Morbidity
Alopecia areata involves immune system imbalances that may lead to depression and anxiety.
research Dupilumab: A Review of Present Indications and Off-Label Uses
Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.
research Neuroimmunoregulation of Androgens in the Adrenal Gland and the Skin
Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.
research Emerging Treatments in Alopecia
New alopecia treatments aim for better results and fewer side effects.
research Current and Potential Agents for the Treatment of Alopecia Areata
Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.
research Studying the Genetic Predisposing Factors in the Pathogenesis of Acne Vulgaris
Genetics play a role in acne, but how exactly they contribute is not fully understood.
research Epidermal Keratinocytes Initiate Wound Healing and Pro-Inflammatory Immune Responses Following Percutaneous Schistosome Infection
Epidermal keratinocytes start wound healing and inflammation after schistosome infection.
research Toxic Shock Syndrome: Recent Developments in Pathogenesis
Toxic shock syndrome is caused by a complex interaction of bacterial toxins and the immune system, and understanding this can help improve diagnosis and treatment.
research A Novel Therapeutic Paradigm for Patients with Extensive Alopecia Areata
New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.
research Advanced Inhibition of Undesired Human Hair Growth by PPARγ Modulation
GMG-43AC may help reduce unwanted hair growth and treat certain hair loss conditions.