research Janus Kinase Inhibitor Increases Hair Growth by Increasing Beta-Catenin Activity in Outer Root Sheath Cells
JAK inhibitors help hair growth by boosting beta-catenin activity in hair root cells.
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research Translation-Dependent Skin Hyperplasia Promoted by Type 1/17 Inflammation in Psoriasis
Type 1/17 inflammation in psoriasis increases skin cell growth due to a molecule that could be a new treatment target.
research The Possible Role of PTEN-Induced Kinase 1-Mediated Mitophagy in Regulating Inflammasome Activation in the Pathogenesis of Alopecia Areata
Activating mitophagy may help manage a key immune response involved in the hair loss condition alopecia areata.
research Chronic Graft-Versus-Host Disease Exhibits Distinct Th1-Skewing and Barrier Abnormalities in the Skin
Chronic graft-versus-host disease in the skin shows strong Th1 immune response and unique barrier issues.
research Lichen Planus – A Refractory Autoimmune Disorder
Lichen planus is a chronic autoimmune disease that is hard to treat and more common in women.
research Author Response: Involvement of ILC1-Like Innate Lymphocytes in Human Autoimmunity, Lessons from Alopecia Areata
ILC1-like cells may contribute to hair loss in alopecia areata.
research Editor's Evaluation: Involvement of ILC1-Like Innate Lymphocytes in Human Autoimmunity, Lessons from Alopecia Areata
ILC1-like cells can independently cause alopecia areata by affecting hair follicles.
research Decision Letter: Involvement of ILC1-Like Innate Lymphocytes in Human Autoimmunity, Lessons from Alopecia Areata
ILC1-like cells may contribute to hair loss in alopecia areata and could be new treatment targets.
research Tyrosine Kinase 2 Inhibition Rescues Hair Follicles From IL-12-Mediated Immune Privilege Collapse And Reverses Human Alopecia Areata In A Humanized Mouse Model
Inhibiting TYK2 can restore hair growth in alopecia areata.
research Case Report: Successful Treatment of Alopecia Universalis With Tofacitinib and Increased Cytokine Levels: Normal Therapeutic Reaction or Danger Signal?
Tofacitinib regrew hair in a man with total hair loss but raised cytokine levels, needing more research on possible side effects.
research SnapshotDx Quiz: April 2022
Discoid Lupus Erythematosus causes scalp plaques that can lead to hair loss, and antimalarial drugs are effective treatments.
research Selective Inhibition of Tyrosine Kinase 2 Prevents and Restores Interleukin-12-Induced Hair Follicle Immune Privilege Collapse: A Novel Approach to Alopecia Areata Therapy?
Blocking IL-12 can help treat alopecia areata by preventing hair follicle immune issues.
research Rare Presentation of Concomitant Alopecia Areata and Vitiligo in a Teenager
A teenager had both alopecia areata and vitiligo, which are rare to occur together.
research Updates in the Pathogenesis of Alopecia Areata
Alopecia areata is an autoimmune condition causing hair loss, linked to genetic factors and immune system issues, with no cure yet.
research A Perspective on Predictive Markers of Alopecia
Certain immune molecules and stress affect hair loss, and while genes play a role, more research is needed to fully understand and treat it.
research Innate Lymphoid Cells Type 1 May Be New, Non-Antigen-Specific Player in the Pathogenesis of Alopecia Areata
Innate lymphoid cells type 1 may contribute to alopecia areata.
research Mouse Models of Alopecia Areata: C3H/HeJ Mice Versus the Humanized AA Mouse Model
The humanized AA mouse model is better for testing new alopecia areata treatments.
research Effects of Crataegi Fructus Water Extract on Hair Growth and Gene Expression in Dermal Papilla Cells
Crataegi Fructus water extract helps hair grow better and thicker.
research Effect of Lithocholic Acid as a Ligand of Vitamin D Receptor on Hair Growth in Alopecia
Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.
research Influence of Gushen Shengfa Pills Combined with Wuling Capsules on Th1/Th2 Cytokines in Patients with Alopecia Areata
Gushen Shengfa pills and Wuling capsules are more effective for hair growth and sleep quality than the control treatment.
research Effects of Yikgeebohyul-Tang on Hair Growth Promotion and Cytokine Changes in C57BL/6 Mice
Yikgeebohyul-tang promotes hair growth and could help treat hair loss.
research Correspondence
A man's skin cancer improved and some of his hair grew back after treatment with a special light therapy and a medication.
research Janus Kinase Inhibitors Versus Other Biological Treatments in Alopecia Areata
Janus kinase inhibitors show promise in treating alopecia areata but need more safety research.
research Alopecia Universalis Following Interferon Alfa-2b and Ribavirin Treatment for Hepatitis C
A woman lost all her body hair after hepatitis C treatment, but it started to grow back a year after stopping the treatment.
research Bullous Lesions at Polyethylene Glycol Interferon-Alpha-2a Inoculation Site in a Hepatitis C Virus-Infected Subject
A patient developed a blister at the injection site after hepatitis C treatment.
research Tofacitinib Treatment of Inflammatory Skin Conditions in Patients With Down Syndrome
Tofacitinib helps improve skin conditions in people with Down syndrome, especially alopecia areata.
research Predictive Factors for Adverse Dermatological Events During Pegylated/Interferon Alpha and Ribavirin Treatment for Hepatitis C
Older age, pre-existing skin conditions, cirrhosis, and pegylated interferon use increase the risk of skin issues during hepatitis C treatment.
research Lymphocytes, Neuropeptides, And Genes Involved In Alopecia Areata
Alopecia areata is an autoimmune disease where T cells attack hair follicles.
research Multiple Sclerosis Disease-Modifying Therapies: Adverse Effect Surveillance and Management
The document concludes that managing side effects of MS therapies is crucial for treatment success and patient adherence.
research An Integrated Model of Alopecia Areata Biomarkers Highlights Both Th1/Th2 Upregulation, with Stronger Correlations Between Th2 Activation and Disease Severity
Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.