April 2017 in “Journal of Investigative Dermatology” This study found that fisetin, a dietary flavonoid, significantly improved psoriasiform skin lesions in mice by promoting cell differentiation, inhibiting proliferation, and modulating inflammatory responses.
1 citations
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December 2016 This review discusses the approved uses and adverse reactions of JAK inhibitors, noting their importance in treating various conditions but highlighting significant hematological and immunological risks.
1 citations
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September 2023 in “International Journal of Dermatology” In this study conducted at a tertiary dermatological clinic, researchers identified and described the clinical, dermoscopic, and histopathological features of preclinical folliculitis keloidalis, including novel dermoscopic findings such as perifollicular scale, which was associated with fibrosis.
January 2023 in “Applied sciences” This study found that co-administering sasam-Kyeongokgo with gefitinib enhanced gefitinib's anti-tumor activity and exhibited favorable anti-cachexia effects in mice with non-small-cell lung cancer.
12 citations
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January 2014 in “Cell structure and function” This study suggests that specific combinations of human type I and II hair keratins, particularly K35-K85 and K36-K81, have distinct in vitro assembly properties that are significant for macrofibril formation.
April 2020 in “The FASEB journal” In in-vitro experiments, this study found that poncirin showed higher inhibitory activity against JAK3 than tofacitinib, suggesting potential for alopecia areata treatment.
91 citations
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December 2000 in “The journal of cell biology/The Journal of cell biology” This study reports that expressed mouse type Ia and type IIa trichocyte keratins were successfully assembled into intermediate filaments in vitro, while also suggesting that disulfide bond cross linking enhances their stability.
January 2012 in “Zhongguo shengwuzhipinxue zazhi” This study found that a complex filling material made from autologous skin fibroblasts and hair keratin significantly improved the appearance of facial wrinkles, suggesting potential for clinical cosmetic applications.
March 2018 in “Suez Canal University Medical Journal” This review examines targeting the JAK-STAT pathway in inflammatory skin diseases, highlighting existing JAK inhibitors and potential developments, but presents no new experimental or clinical results.
15 citations
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April 2001 in “Journal of Dermatological Science” This study found that KF19418 stimulated hair follicle growth in vitro and accelerated hair regrowth in a mouse alopecia model, with effects comparable to minoxidil.
September 2024 in “BMJ Case Reports” This case report highlights an atypical presentation of favus in an immunocompetent adult, where a psoriasiform plaque over the 'bindi' area was successfully treated with systemic itraconazole, achieving complete resolution without relapse. Simple stains proved essential for diagnosis in this resource-limited setting.
June 2023 in “Medical records-international medical journal” This study observed that IGF-1R expression significantly decreased in basal keratinocytes of sacrococcygeal pilonidal sinus tissues, suggesting a potential role in its etiology, although further data are needed to evaluate its treatment implications.
6 citations
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January 2014 in “Genetics and Molecular Research” This study constructed a hair follicle-specific expression vector for IGFBP-5 in Inner Mongolia Cashmere goat cells, allowing for future functional genetic analyses and potential use in nuclear transfer.
March 2024 in “Poster presentations” This case report describes a 43-year-old woman diagnosed with both Kikuchi-Fujimoto disease and systemic lupus erythematosus, who showed clinical improvement after treatment with glucocorticoids and hydroxychloroquine, highlighting the rare coexistence of these conditions and the ongoing uncertainty about the precise cause of Kikuchi-Fujimoto disease.
Infliximab was effective in treating a scalp condition that did not respond to other treatments.
40 citations
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December 2016 in “Journal of Dermatological Treatment” This study reviewed the role of the JAK/STAT signaling pathway in skin diseases and the potential of JAK inhibitors for treating conditions like psoriasis and atopic dermatitis. Although the findings are promising, the authors concluded it is premature to establish their place in dermatological treatments.
1 citations
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January 2025 in “Burns & Trauma” This study found that targeting the molecule Midkine may reduce pain and itching in keloid patients by inhibiting specific Schwann cell activities contributing to these symptoms.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, treatment with oral JAK inhibitors was associated with improved disease outcomes in 80.6% of patients with refractory lichen planopilaris over a mean duration of 5 months.
November 2023 in “Deleted Journal” In this study, the researchers found no superiority of combining 308-nm excimer laser with intralesional corticosteroid over corticosteroid alone for treating frontal fibrosing alopecia, and reported side effects such as erythema and postinflammatory hyperpigmentation in both treatment groups.
July 2015 in “International Society of Hair Restoration Surgery” This project by the International Society of Hair Restoration Surgery reviews best practices in hair restoration surgery and reports no new research findings.
1 citations
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November 2022 in “International journal of trichology” This case report describes a 6-year-old girl with IFAP syndrome who showed good improvement in cutaneous symptoms after one month of acitretin treatment.
This study identified significant differences in KIR gene profiles between SLE patients and controls, suggesting that specific KIR genes could serve as biomarkers for disease severity in Indian SLE patients.
November 2020 in “Journal of the American Academy of Dermatology” Intense pulsed light with radiofrequency showed mixed results in improving quality of life for hidradenitis suppurativa patients, with no clinical improvements.
September 2019 in “Journal of Investigative Dermatology” This study found that using human induced pluripotent stem cells (iPSC) carrying the causal mutation of Epidermolysis Bullosa simplex provides a robust model for understanding its molecular mechanisms and testing potential therapeutic targets.
June 2026 in “IP Indian Journal of Clinical and Experimental Dermatology” This bibliometric analysis of the IP Indian Journal of Clinical and Experimental Dermatology reveals a steady annual publication growth rate of 5.49% from 2019 to 2025, moderate citation impact, and limited international collaboration.
1 citations
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July 2024 in “British Journal of Dermatology” This study found that inhibiting EGFR and MEK in hair follicles may lead to a partial collapse of the immune privilege in the follicles and increased secretion of IL-33.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that women with female pattern hair loss had significantly lower serum IGF-1 levels than controls, suggesting a possible role for IGF-1 in this condition.
March 2026 in “Journal for ImmunoTherapy of Cancer” This paper reports insights from an Expert Panel convened by the Society for Immunotherapy of Cancer on managing immune-related adverse events (irAEs) following immune checkpoint inhibitor therapy, highlighting surveillance gaps and the need for a comprehensive irAE registry to improve post-treatment care for cancer survivors.
September 2022 in “XXXIX Congresso Brasileiro de Reumatologia” In this case report, a 42-year-old woman with cutaneous dermatomyositis showed significant improvement, including reduction of erythema, pruritus, and scaling, after starting JAK inhibitor tofacitinib, especially when conventional systemic treatments failed and intravenous immune globulin wasn't viable.
8 citations
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December 2009 in “Journal of The European Academy of Dermatology and Venereology” This article discusses a novel mutation in the FERMT1 gene identified in a Spanish family with Kindler’s syndrome but reports no new clinical results.