May 2026 in “International Journal of Dermatology” This study investigated a unique frontal fibrosing alopecia-like presentation of alopecia areata, finding that patients experienced an insidious, chronic course with limited scalp hair regrowth, and showed a lower response to systemic corticosteroids compared to patchy alopecia areata.
98 citations
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November 1999 in “Dermatology Online Journal” This review discusses the effects of IGF-1 on hair follicle cell proliferation and differentiation, highlighting its roles in paracrine signaling, apoptosis prevention, and hair growth, but reports no new clinical results.
4 citations
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January 2022 in “Dermatologic Therapy” In this retrospective analysis, the authors reported that off-label tofacitinib treatment in 35 alopecia areata patients demonstrated safety, with no serious adverse events, and effectiveness, with 83.9% showing significant scalp regrowth and 32.3% achieving near total or total regrowth.
January 2024 in “Journal of Clinical Images and Medical Case Reports” This article discusses frontal fibrosing alopecia as a type of Lichen planopilaris marked by gradual hair loss at the front of the scalp but reports no new clinical results.
April 2018 in “Journal of Investigative Dermatology” In a clinical phase I/IIa study, subcutaneous injections of the peptide FOL-005 increased hair growth by 8% and were safe for treating alopecia.
26 citations
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October 2017 in “PubMed” According to this study, systemic retinoids, specifically oral isotretinoin and acitretin, were more effective than finasteride in stabilizing the frontal hairline in female patients with frontal fibrosing alopecia, achieving treatment goals in over 70% of cases.
9 citations
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July 2019 in “Dermatologic therapy” In this case report, a patient with frontal fibrosing alopecia and lichen planus responded well to treatment with alitretinoin, suggesting a potential therapeutic role for alitretinoin in similar cases.
January 2016 in “Indian dermatology online journal” This case study diagnosed a 60-year-old woman with frontal fibrosing alopecia after histopathological analysis showed characteristic scarring patterns in the hairline area.
30 citations
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May 2016 in “International Journal of Cosmetic Science” This study found that apoptosis was more prevalent in hair follicles of women with female pattern hair loss, particularly in miniaturized follicles, and was associated with follicular inflammation.
2 citations
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March 2019 in “PubMed” This article discusses various forms of alopecia and introduces Biofibre® as a current technique for addressing hair loss, without reporting new clinical results.
238 citations
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November 2016 in “Journal of The American Academy of Dermatology” In this study, tofacitinib was reported to improve scalp hair regrowth in patients with severe alopecia areata, alopecia totalis, and alopecia universalis, showing a higher response in alopecia areata.
June 2025 in “International Journal of Science and Research (IJSR)” This study found that oral tofacitinib at a 5mg twice daily dosage was effective in treating recalcitrant alopecia areata, showing significant improvement in hair regrowth and a 27% reduction in SALT scores over six months, with minimal side effects among the 19 patients monitored.
1 citations
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August 2018 in “Journal of the American Academy of Dermatology” A young woman developed facial bumps before hair loss, which is unusual for her condition.
October 2024 in “International Journal of Research in Dermatology” In this retrospective study, tofacitinib showed promise as a treatment for alopecia areata, with 46.5% of patients experiencing a very good response and minimal adverse effects, suggesting it could be a primary option for moderate to severe cases.
April 2026 in “Journal of Dermatological Treatment” This study concluded that in female pattern hair loss patients, CGF and i-PRF treatments were more effective than PRP in increasing target area hair count, with i-PRF having the lowest adverse event rate.
September 2024 in “BMJ Case Reports” This case report highlights an atypical presentation of favus in an immunocompetent adult, where a psoriasiform plaque over the 'bindi' area was successfully treated with systemic itraconazole, achieving complete resolution without relapse. Simple stains proved essential for diagnosis in this resource-limited setting.
August 2024 in “Indian Journal of Dermatology Venereology and Leprology”
January 2024 in “The Egyptian Journal of Hospital Medicine” This study found that A-FABP serum levels were significantly higher in male patients with androgenetic alopecia compared to controls, and the authors concluded that A-FABP could serve as a biomarker for early detection of this condition.
September 2025 in “Current Issues in Molecular Biology” This study highlights IGF-1's role in promoting hair follicle proliferation, vascularization, and growth, suggesting its potential as a treatment target for hair loss disorders like androgenetic alopecia, though more research on delivery methods and long-term effects is needed.
May 2012 in “CRC Press eBooks” Some patients on anti-TNF drugs experience a type of hair loss called TAIAPA.
1 citations
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February 2025 in “Pediatric Dermatology” This study found that oral tofacitinib achieved significant hair regrowth in children with moderate to severe alopecia areata, with 72.2% reaching a 75% improvement and 52.8% achieving complete regrowth, though some patients did not respond and further research is needed on the treatment's long-term effects.
January 2018 in “Archives of general internal medicine” The document concludes that automatic biofiber hair implant is a new method for improving hair growth.
17 citations
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January 2019 in “Dermatologic Therapy” The article in Dermatologic Therapy discusses clinical experiences with using tofacitinib to treat alopecia areata in 63 patients, but no specific results are reported in the abstract.
7 citations
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July 2021 in “The Journal of Dermatology” This study in Asian females found that higher use of moisturizers and sunscreen among FFA patients may reflect appearance concerns rather than indicating a direct link to the disease mechanism.
5 citations
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January 1991 in “Drugs of The Future” December 2022 in “Zenodo (CERN European Organization for Nuclear Research)” In this report, a 14-year-old female with stubborn alopecia areata was successfully treated with oral tofacitinib, indicating its potential effectiveness for severe cases.
November 2020 in “Dubai medical journal” This case report described a 24-year-old with alopecia totalis who saw full scalp hair regrowth by the 9th month while using oral tofacitinib, which was well-tolerated and did not show serious adverse effects. Longer-term studies are needed to confirm its overall effectiveness for alopecia totalis.
25 citations
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December 2017 in “Facial Plastic Surgery” This study observed that combining high-potency steroids with pimecrolimus might effectively stabilize hairline recession in frontal fibrosing alopecia patients.
July 2018 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that finasteride delivered through a nano-transferosomal gel showed improved penetration through skin layers compared to a conventional gel, suggesting a potential alternative for oral administration.
March 2024 in “Current materials science” This study explores the various properties of the flavonoid fisetin, highlighting its potential therapeutic applications due to its ability to modulate numerous biological pathways, suggesting benefits in conditions like inflammation, cancer, and neurodegenerative diseases.