Efficacy of Isotretinoin and Acitretin in Treatment of Frontal Fibrosing Alopecia: Retrospective Analysis of 54 Cases

    October 2017 in “ PubMed ”
    Adriana Rakowska, Agnieszka Gradzińska, Małgorzata Olszewska, Lidia Rudnicka
    TLDR Isotretinoin and acitretin may effectively stabilize the hairline in patients with frontal fibrosing alopecia.
    This retrospective study evaluated the efficacy of systemic retinoids in treating frontal fibrosing alopecia (FFA) in 54 female patients. The patients were treated with oral isotretinoin (29 patients), acitretin (11 patients), or finasteride (14 patients) over a period of 12-16 months. The primary goal was to halt disease progression after 12 months, which was achieved by 76% of isotretinoin, 73% of acitretin, and 43% of finasteride patients. The secondary goal, maintaining disease stabilization post-treatment, was achieved by 72% of isotretinoin, 73% of acitretin, and 43% of finasteride patients. The study concluded that systemic retinoids could be beneficial for stabilizing the frontal hairline in FFA patients.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 36 results

      community Isotretinoin and Tretinoin difference

      in Product  2 upvotes 1 week ago
      Isotretinoin and tretinoin are different; isotretinoin can cause hair loss and has more side effects. Tretinoin may affect minoxidil absorption, and users suggest waiting before applying minoxidil.

      community Which retinoid for better min absorption?

      in Product  4 upvotes 2 months ago
      User is on vacation in Greece and wants to buy tretinoin or isotretinoin to improve Minoxidil absorption. They are considering isotretinoin since it is available over-the-counter in Greece but requires a prescription back home.

      community Dut/Minox/Needling to Dut/Oral Minox/Tretinoin/Needling

      in Minoxidil  3 upvotes 6 months ago
      The user had been using Minoxidil and Dutasteride with micro-needling but experienced hair loss after switching Minoxidil brands. Their doctor prescribed oral Minoxidil and Tretinoin, but the pharmacist suggested isotretinoin might be a more cost-effective alternative.

      community Seborrheic dermatitis - can it cause long-term shedding (or telogen effluvium)?

      in Advice  6 upvotes 4 years ago
      A user is experiencing significant hair loss and scalp issues despite using Minoxidil, finasteride, and RU58841 since 2017. They switched to oral Minoxidil and are now on isotretinoin and topical corticosteroids for seborrheic dermatitis but continue to lose hair and seek advice on whether inflammation or treatment changes are the cause.

    Related Research

    1 / 1 results