Therapeutic Potential of Oral Tofacitinib in Alopecia Areata: A Retrospective Study

October 2024 in “ International Journal of Research in Dermatology ”

B. S. Chandrashekar, Varsha R. Koti, Madura Chandu, Chaithra Shenoy, Abhijna Chandar, M. S. Roopa, Nagamani Narayana

tofacitinib alopecia areata acneiform eruptions

TLDR Tofacitinib is a promising and safe treatment for moderate to severe alopecia areata.

This retrospective study evaluated the long-term efficacy and safety of oral tofacitinib in 69 patients with various forms of alopecia areata (AA) from January 2017 to October 2022. The results showed that 46.5% of patients had a very good response, and 4.3% had an excellent response, with 44.9% experiencing no recurrence. Minimal adverse effects were reported, such as acneiform eruptions and upper respiratory tract infections. The study concluded that tofacitinib is a promising treatment for moderate to severe AA, with no serious side effects observed, making it a potential primary treatment option.

View this study on ijord.com →

Discuss this study in the Community →

Related Community Posts Join

6 / 6 results

community 22F. Should I even bother getting a biopsy? Is there any point?

7 upvotes 8 years ago

A woman who has been experiencing hair loss for several years, and her question of whether there is any benefit to getting a biopsy to check if it's AGA or diffuse alopecia areata when no cure or very effective treatment exists. Treatments such as spironolactone and Minoxidil/finasteride/RU58841 have previously been discussed.

community Female, 27 years old, shedding/ balding despite being on what is considered to be a effective treatment plan for AGA. Considering Dut (oral) . Please help.

in Finasteride/Dutasteride 27 upvotes 1 month ago

A 27-year-old woman with androgenic alopecia is losing hair despite using oral minoxidil and spironolactone, and is considering dutasteride. She is exploring causes like stress and medication side effects, planning tests, and considering treatment changes.

community What else is good. Besides the big 3.

in Chat 34 upvotes 2 months ago

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

community The shedding caused by Minoxidil is one of the worst things. 2 months apart each picture

in Progress Pictures 290 upvotes 4 months ago

The conversation discusses the severe shedding caused by Minoxidil, with users sharing their experiences and outcomes. Some report eventual regrowth, while others see no improvement or worsening hair loss.

community No hair, don't care! [24/F] :)

61 upvotes 8 years ago

A woman with alopecia universalis shares her positive experience of being bald, finding it freeing and less worrisome. She also discusses her skincare routine using Korean products.

community Finasteride and Oral Minoxidil in Turkey - what I’ve found out

in Finasteride/Dutasteride 10 upvotes 4 months ago

Finasteride is available in Turkey without a prescription, with 1mg tablets costing 800 Turkish lira and 5mg tablets costing 150 lira. Oral minoxidil capsules were found at Cerrahpaşa nur eczanesi, also without a prescription.

Related Research

2 / 2 results

research Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child

April 2019 in “International journal of research in dermatology”

A child with rough nails also had hair loss and allergies.

research Successful Treatment of Severe Alopecia Areata With Oral or Topical Tofacitinib

4 citations, July 2018 in “PubMed”

Oral and topical tofacitinib can help regrow hair in people with severe alopecia areata.