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Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

Stress hormones like cortisol may trigger psoriasis flare-ups.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Low birthweight and rapid weight gain after birth may increase the risk of developing polycystic ovary syndrome.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Blocking 11β-HSD1 can lessen the harmful effects of glucocorticoids on hair growth cells.

Melatonin and cortisol affect mink winter hair growth, but β-endorphin levels do not.

Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

PCOS may have evolved as an advantage in past environments with food scarcity.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Spironolactone treatment increases the amount of testosterone available in the body.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Human skin can make serotonin and melatonin.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Androgens can help prevent memory problems caused by apoE4.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.