research The Angiogenic Potential of Mesenchymal Stem Cells from the Hair Follicle Outer Root Sheath
Hair follicle stem cells are promising for blood vessel formation and tissue repair.
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research Paracrine Secreted Frizzled-Related Protein 4 Inhibits Melanocyte Differentiation in Hair Follicle
A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
research Cellular Heterogeneity and Plasticity of Skin Epithelial Cells in Wound Healing and Tumorigenesis
Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.
research Inflammatory Loops in the Epithelial-Immune Microenvironment of the Skin and Skin Appendages in Chronic Inflammatory Diseases
Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.
research Transient Calcium Entry by Plasmalogen-Mediated Activation of Receptor Potential Cation Channel Promotes AMPK Activity
Plasmalogens activate a channel in cells that may stimulate hair growth.
research Adipose-Derived Stem Cells in Skin Diseases, Wound Healing, and Skin Defects: A Review
Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.
research High-Throughput and Direct Measurement of Androgen Levels Using Turbulent Flow Chromatography Liquid Chromatography-Triple Quadrupole Mass Spectrometry to Discover Chemicals That Modulate Dihydrotestosterone Production in Human Prostate Cancer Cells
Researchers found four natural compounds that can change DHT levels in prostate cancer cells.
research Exosomes Derived Stem Cells as a Modern Therapeutic Approach for Skin Rejuvenation and Hair Regrowth
Exosomes from stem cells may help rejuvenate skin and regrow hair, but more research is needed.
research Fresh Umbilical Cord Blood as a Source of Multipotent Stem Cells: Collection, Banking, Cryopreservation, and Ethical Concerns
Umbilical cord blood is a valuable source of stem cells for medical treatments, but its use is less common than other transplants, and there are ethical issues to consider.
research Trapa Bispinosa Roxb. Pericarp Extract Exerts 5α-Reductase Inhibitory Activity in Castrated Benign Prostatic Hyperplasia Model Mice
Trapa bispinosa Roxb. extract may help reduce prostate size and cell growth in BPH.
research Revolutionizing Radiotoxicity Management with Mesenchymal Stem Cells and Their Derivatives: A Focus on Radiation-Induced Cystitis
Mesenchymal stem cells could help treat radiation-induced bladder damage but more research is needed to overcome current limitations.
research Editor's Evaluation: Role of Distinct Fibroblast Lineages and Immune Cells in Dermal Repair Following UV Radiation-Induced Tissue Damage
Different types of sun exposure damage skin cells and immune cells, with chronic exposure leading to more severe and lasting damage.
research Connecting Signaling Dynamics With Cell Fates In Live Mice
Stem cells control their future role by changing ERK signal timing, affecting tissue regeneration and cancer.
research Knockout of mTOR/Akt Inhibitor REDD1 Results in Hair Cycle-Independent Dermal Adipose Expansion by Promoting Adipocyte Differentiation
Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.
research Targeting mTORC1 Suppresses Proliferation of Keratinocyte Stem Cells and Inhibits Skin Tumor Promotion in Mice
Blocking mTORC1 reduces skin tumor growth in mice.
research Role of Stem Cells in Skin Maintenance, Regeneration, and Repair: Focus on Epidermis and Pilosebaceous Units
The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
research Editors' Picks
Small molecule DMF improves psoriasis and multiple sclerosis, adult skin cells can be made to grow new hair, certain skin cells initiate hair growth, IL-17C controls gut health and can cause skin inflammation, and skin cells produce IL-17 that can lead to psoriasis.
research Abstracts Presented at the 12th Joint Meeting of the International Society of Dermatopathology, March 4-5, 2009, Marines Memorial Club & Hotel, San Francisco, CA, USA
Mast cells play a significant role in hair loss conditions like male pattern hair loss and alopecia areata.
research Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors
Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.
research Epigenetic Control of Adult Stem Cell Function
Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
research Epidermal Stem Cell Diversity and Quiescence
Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
research Epidermal Stem Cells in Wound Healing and Their Clinical Applications
Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
research Cell Death in the Skin: Mechanisms and Implications
Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
research Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT Signaling Axis
PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
research Inducible Deletion of Epidermal Dicer and Drosha Reveals Multiple Functions for miRNAs in Postnatal Skin
Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
research Finasteride Treatment Inhibits Adult Hippocampal Neurogenesis in Male Mice
Finasteride reduces new brain cells in male mice, possibly causing depression.
research The HPV16 Oncogenes Cause Aberrant Stem Cell Mobilization
HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.
research PTEN Mediates Activation of Core Clock Protein BMAL1 and Accumulation of Epidermal Stem Cells
PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.
research The Epithelial Stem Cell Niche in Skin
Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
research Optimization of the Reconstruction of Dermal Papilla-Like Tissues Employing Umbilical Cord Mesenchymal Stem Cells
Using umbilical cord stem cells can help create hair-growing tissues more affordably.