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      Androgen Conjugates: Physiology and Clinical Significance

      research Androgen Conjugates: Physiology and Clinical Significance

      54 citations , February 1993 in “Endocrine reviews”
      This review examines the physiological role of androgen conjugates in cutaneous androgen metabolism and questions their association with hirsutism, without presenting new clinical findings.
      Hirsutism in Young Girls: Beyond PCOS

      research 7745 Hirsutism in young girls, Beyond PCOS

      October 2024 in “Journal of the Endocrine Society”
      This case study describes three young females with hirsutism who were diagnosed with different underlying conditions—late-onset congenital adrenal hyperplasia, idiopathic hirsutism, and polycystic ovary syndrome with ovarian thecosis—highlighting the need for reevaluation if initial treatments are ineffective.

      research Treatment of hirsutism and acne in hyperandrogenism

      54 citations , June 2006 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism”
      This review discusses the management of hirsutism and acne in women with polycystic ovary syndrome, highlighting the partial effectiveness of current treatments and suggesting a combined approach of medication and hair removal.

      research Postmenopausal hyperandrogenism

      15 citations , May 2021 in “Climacteric”
      This review discusses the characteristics, diagnostic challenges, and management options for postmenopausal hyperandrogenism but reports no new clinical results; it highlights the importance of distinguishing potential androgen-producing tumors or hyperandrogenic disorders.
      Treatment of Hyperandrogenism in Polycystic Ovary Syndrome

      research Treatment of hyperandrogenism in polycystic ovary syndrome

      1 citations , October 2010 in “Cambridge University Press eBooks”
      This review discusses strategies for managing dermatological symptoms of hyperandrogenism in PCOS by reducing androgen levels and actions, and reports no new clinical results.
      Commentary: Unroofing for Hidradenitis Suppurativa, Why and How

      research Commentary: Unroofing for hidradenitis suppurativa, why and how

      17 citations , August 2010 in “Journal of the American Academy of Dermatology”
      This article discusses the surgical technique of "deroofing" for hidradenitis suppurativa, highlighting its advantages over traditional methods but reports no new clinical results; the authors emphasize the importance of dietary management as part of treatment.
      Hirsutism: A Psychological Analysis

      research ‘Hirsutism’: A Psychological Analysis

      64 citations , May 2003 in “Journal of health psychology”
      This study found that women with PCOS reported higher overall psychological distress, but there was no significant link between their perceived hirsutism and this distress.

      research Spironolactone Therapy for Hirsutism in a Hyperandrogenic Woman

      39 citations , November 1978 in “Annals of internal medicine”
      This brief report discusses spironolactone used as a treatment for hirsutism in a hyperandrogenic woman, offering no new clinical findings and focusing on its antiandrogenic properties.

      research Cyproterone acetate for hirsutism

      78 citations , October 2003 in “Cochrane library”
      This review found that adding cyproterone acetate to estradiol showed a subjective improvement in hirsutism versus placebo, but comparisons with other therapies revealed no clinical differences.
      Cutaneous Manifestations and Their Relationship with Serum Testosterone and DHEAS Levels in Women with Polycystic Ovary Syndrome: A Cross-Sectional Clinical Study

      research Cutaneous Manifestations and Their Relationship with Serum Testosterone and DHEAS Levels in Women with Polycystic Ovary Syndrome: A Cross‑Sectional Clinical Study

      February 2026 in “Zenodo (CERN European Organization for Nuclear Research)”
      In this cross-sectional study at a tertiary care hospital, researchers found a significant correlation between cutaneous manifestations like hirsutism and acne and biochemical hyperandrogenism levels in women with PCOS, suggesting these skin conditions can predict elevated androgen levels.
      Spironolactone in Hidradenitis Suppurativa: A Single-Center Study

      research Spironolactone in hidradenitis suppurativa: a single-center

      3 citations , March 2024 in “International Journal of Women’s Dermatology”
      This study observed that spironolactone improved hidradenitis suppurativa in over 80% of female patients at 3 and 6 months, with no significant differences in response due to menstrual flares or polycystic ovarian syndrome, but mild adverse events were reported.
      Managing Cutaneous Manifestations of Hyperandrogenic Disorders

      research Managing Cutaneous Manifestations of Hyperandrogenic Disorders

      22 citations , January 2002 in “Treatments in endocrinology”
      This review examines the role of androgens in cutaneous disorders and the potential therapeutic effects of different oral contraceptives, noting variations in individual responses and the influence of genetic and local factors but reports no new clinical results.
      Endocrinologic Aspects of Hidradenitis Suppurativa

      research Endocrinologic Aspects of Hidradenitis Suppurativa

      45 citations , November 2015 in “Dermatologic Clinics”
      This review discusses the potential hormonal and metabolic factors influencing hidradenitis suppurativa and highlights the need for further research to explore hormonal dysregulation's role in the disease.
      Hirsutism

      research Hirsutism

      10 citations , May 1995 in “Journal of General Internal Medicine”
      Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.

      research Is idiopathic hirsutism idiopathic?

      16 citations , March 2022 in “Clinica Chimica Acta”
      This study suggests that women with idiopathic hirsutism have increased 5α-reductase activity, indicated by elevated levels of 3α-diol glucuronide; further research is needed to assess its clinical biomarker potential.
      The Evaluation and Management of Hirsutism

      research The Evaluation and Management of Hirsutism

      11 citations , May 2003 in “Obstetrics and gynecology (New York. 1953. Online)/Obstetrics and gynecology”
      This review explores the evaluation and treatment of hirsutism, emphasizing a systematic approach to uncovering its causes and recommending combination therapies for effective management, but presents no new results.

      research Steroid inhibitors of androgen-potentiated actions on skin

      4 citations , July 1983 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry”
      In this study, hirsute women treated with cyproterone acetate and ethinyloestradiol experienced significant reductions in sebum secretion and hair growth after several months.

      research Hirsutism: management and therapeutic options

      January 2001
      This review discusses the evaluation and treatment options for hirsutism, including both cosmetic and pharmacological interventions, but reports no new research findings.
      Androgen Excess in Women: Experience with Over 1000 Consecutive Patients

      research Androgen Excess in Women: Experience with Over 1000 Consecutive Patients

      947 citations , February 2004 in “The Journal of Clinical Endocrinology and Metabolism”
      In this study, polycystic ovary syndrome was the most prevalent cause of androgen excess, and suppressive hormonal therapy improved hirsutism, menstrual dysfunction, and acne in most patients, though side effects were common.
      Iris Germanica L. Rhizome-Derived Exosomes Ameliorated Dihydrotestosterone-Damaged Human Follicle Dermal Papilla Cells Through the Activation of Wnt/β-Catenin Pathway

      research Iris germanica L. Rhizome-Derived Exosomes Ameliorated Dihydrotestosterone-Damaged Human Follicle Dermal Papilla Cells Through the Activation of Wnt/β-Catenin Pathway

      April 2025 in “International Journal of Molecular Sciences”
      In this study, exosomes derived from Iris germanica L. rhizomes (Iris-exosomes) were reported to alleviate oxidative stress and improve mitochondrial function in human follicle dermal papilla cells by activating the Wnt/β-catenin signaling pathway, suggesting potential benefits for hair loss treatment.