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This study suggests that idiopathic hirsutism may involve higher local androgen synthesis despite normal serum androgen levels, challenging its categorization as idiopathic.

In this study, serum omentin-1 levels were higher in females with idiopathic hirsutism compared to those with hirsutism and polycystic ovary syndrome, suggesting it may help distinguish between these conditions.

This study found that sebaceous glands predominantly exhibit oxidative activity of the type 2 17β-hydroxysteroid dehydrogenase isozyme, which is not inhibited by 13-cis retinoic acid.

In this study, hydrosurgery for axillary osmidrosis was found to be efficient with fewer postoperative complications compared to the traditional two-incision method, showing lower rates of necrosis and scar formation, and achieving high patient satisfaction over a 24-36 month follow-up.

In this study, niacinamide 4% and desonide 0.05% emulsions significantly improved axillary hyperpigmentation in women, with desonide demonstrating a superior depigmenting effect compared to niacinamide and placebo.

This study reports that 11β-HSD1 activity in human skin increases with age and photoexposure, potentially contributing to skin aging and the effects of glucocorticoids.

This study evaluated Humulus lupulus (hops) extract in cosmetic formulations and found it to maintain antioxidant and anti-irritant properties, reducing erythema by 10% after three weeks of use, supporting its potential for skin health improvement in plant-based cosmetics.

This case report described a 62-year-old postmenopausal woman with hirsutism whose symptoms improved after a hysterectomy and bilateral oophorectomy, revealing bilateral ovarian hyperthecosis.

This review discusses female hyperandrogenism, focusing on its diagnosis, differential diagnoses, and individualized treatment approaches to improve patient health and quality of life, and reports no clinical results.

This study found that plasma 3 alpha-diol glucuronide was markedly elevated in women with idiopathic hirsutism, suggesting it may be a marker of peripheral androgen action.

This case study reported on a 62-year-old woman with ovarian hyperthecosis, which caused symptoms like hirsutism and elevated testosterone; after bilateral oophorectomy, her symptoms improved, suggesting the importance of considering this rare condition in hyperandrogenism diagnosis for postmenopausal women.

In this study, no significant differences in hidradenitis suppurativa severity or testosterone levels were found between women with and without polycystic ovary syndrome, suggesting PCOS does not predict poor prognosis in HS patients.

This article discusses how activating the hexosamine pathway may enhance skin homeostasis by increasing hyaluronic acid secretion and supporting hair follicle stem cell self-renewal, but reports no new results.

This study concluded that a regimen of transdermal estradiol and oral medroxyprogesterone acetate effectively reduces hirsutism while minimizing side effects in women with polycystic ovary syndrome.

In this study, researchers developed a delivery system using a deep eutectic solvent to improve hydroxytyrosol absorption for hair regrowth, achieving over threefold greater skin penetration compared to aqueous solutions and demonstrating its effectiveness and biocompatibility in hair regrowth and ROS-scavenging tests.

The antiandrogen 11α-hydroxyprogesterone effectively reduces skin oil and cholesterol when applied to the skin.

This report describes a rare case of elevated serum DHEAS levels in a postmenopausal woman, linked to an ovarian sex cord-stromal tumor rather than the adrenal glands, challenging common assumptions about androgen sources.

In this study, bilateral oophorectomy was reported as an effective treatment for normalizing androgen levels and resolving hypersexuality and related symptoms in a post-menopausal woman with ovarian hyperthecosis, suggesting its importance in addressing excess androgen production in such cases.

In this study on rat dermal papilla cells, hydroxytyrosol, an antioxidant found in olive oil, was reported to protect against oxidative stress, reduce inflammation, and enhance hair growth factors, suggesting its potential to prevent hair loss.

This study found that Orthosiphon stamineus extract significantly stimulated dermal papilla cell proliferation and enhanced hair growth in an ex vivo model of androgenic alopecia compared to vehicle-treated controls.

This review discusses female hyperandrogenism, detailing diagnostic criteria and treatment options without reporting new study results; it emphasizes improving health and quality of life for affected women.

In this study, researchers found that Ectoin, derived from halophilic bacteria, can mitigate stress-related skin damage by reducing cortisone's inhibitory effects on essential skin proteins and decreasing UVB-induced glucocorticoid activity, highlighting its potential as a preventative agent for stress-induced skin issues.

This study found that 11α-hydroxyprogesterone is a potent inhibitor of 11βHSD2 in vitro and may serve as a precursor to unique C11α-hydroxy steroids in prostate cancer tissue.

This study observed that dermoscopic features of skin affected by topical corticosteroids and hydroquinone correlated with histopathological changes, highlighting the importance of awareness regarding their long-term adverse effects.

This study reports that hydrocortisone ointment significantly improved eyebrow erythema and hair growth in a 10-year-old with ulerythema ophryogenes.

This study found that ovarian suppression significantly reduced serum testosterone and androstenedione in women with polycystic ovarian syndrome and idiopathic hirsutism, with hair growth rates decreasing more in polycystic ovarian syndrome.

This study found that untreated hirsute patients have lower expression of type 2 17β-HSD mRNA in scalp hairs, indicating potential disturbances in androgen metabolism, compared to treated hirsute patients.

Among women with hirsutism studied, this research found a high prevalence of acne, particularly associated with polycystic ovarian syndrome and endocrine changes.

In this case report, a 55-year-old postmenopausal woman was diagnosed with ovarian hyperthecosis as the cause of her hyperandrogenism after detailed hormonal and imaging investigations, which was successfully treated with bilateral salpingo-oophorectomy, leading to symptom improvement and normalized testosterone levels.

In this study, serum omentin-1 levels were significantly higher in females with idiopathic hirsutism compared to those with PCOS and healthy controls.