38 citations
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January 2002 in “Biological & Pharmaceutical Bulletin” This study reported that the aqueous ethanol extract of Lygodii Spora demonstrated in vitro testosterone 5alpha-reductase inhibition and in vivo anti-androgenic activity, potentially due to oleic, linoleic, and palmitic acids.
October 2009 in “Reactions Weekly” A woman developed lupus after taking hydroxyurea for two years.
December 2023 in “ACS Sustainable Chemistry & Engineering” Keratin can be successfully taken from human hair using a mix of choline chloride and ethanolamine.
April 2018 in “Journal of Investigative Dermatology” This study suggests that human hair follicles may operate their own Cori cycle, synthesizing glycogen from lactate under conditions of lactic acidosis.
5 citations
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October 2002 in “PubMed” In this study, the degradation of HHK scaffold particles was linked to the activation and proliferation of satellite cells, which may contribute to new muscle fiber formation.
January 2016 in “Frontiers in Bioengineering and Biotechnology” In this study, a porous keratin hydrogel derived from wool hair demonstrated strong mechanical properties and supported the growth of various animal cells, indicating potential as a scaffold in tissue engineering.
June 2025 in “Academic Medical Journal” This study suggests elevated homocysteine levels may serve as a biomarker for disease severity and vascular risk in cutaneous lupus erythematosus, indicating potential therapeutic benefits from B-vitamin supplementation and lifestyle changes.
5 citations
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January 1990 in “Journal of Society of Cosmetic Chemists of Japan” This study found that permanent wave lotion I extracts proteins from human hair, with molecular weights ranging from 5,000 to 65,000, which may elucidate hair damage mechanisms.
This article reviews the potential benefits of GHK-Cu, EAA, and water-soluble propolis for wound healing, skin tightening, and anti-aging effects, but reports no new clinical results.
May 2026 in “Journal of Medicinal Food” This study found that orally administered hydrolyzed keratin peptide promoted hair growth and enhanced cellular proliferation and antioxidant capacity in mice and human cell models, suggesting its potential as a functional food ingredient for hair health.
February 2026 in “Frontiers in Medicine” This study suggests that combining LMWHA solution and HCO might improve mild to moderate urinary incontinence in women with GSM, potentially offering benefits over HA therapy alone, but further research is needed.
December 2024 in “PubMed”
In this study, researchers found that an injectable solution of low-molecular-weight hyaluronic acid and amino acids significantly improved skin rejuvenation and elasticity in the labia majora of post-menopausal women over 12 weeks, with a reported 25% or greater aesthetic improvement and high patient satisfaction.
May 2025 in “Frontiers in Genetics” This study reported discovering a novel missense variant in a case of autosomal recessive woolly hair in a 31-year-old Chinese woman, which significantly reduced secretion of the encoded protein, likely leading to disease by impairing its hydrolytic function.
1 citations
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October 2022 in “Bioengineering” This study found that adding keratin to a collagen hydrogel improved keratinocyte differentiation compared to a pure collagen hydrogel, particularly when calcium was also present in the media.
4 citations
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July 2024 in “Cureus” In this report, researchers observed that a single treatment using a combination of hyperdiluted calcium hydroxylapatite, platelet-rich plasma, and hyaluronidase improved neck wrinkles and skin laxity in two patients, indicating preliminary evidence for the safety and efficacy of this novel therapy.
3 citations
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January 1982 in “Australian journal of biological sciences” This study found that ethionine significantly inhibited wool growth in sheep, with L- and D-isomers being equally effective, but did not cause hair loss in sucking mice or rats.
7 citations
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February 1998 in “Polymer journal” This study found that the stability of the coiled-coil structure in human hair keratin is maintained by ion-pairing and hydrophobic interactions, which are disrupted as pH approaches 7.0.
January 2017 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that oral collagen peptides increased the expression of genes related to epidermal and hair cycle development in hairless mouse skin.
21 citations
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September 2013 in “Current medicinal chemistry” This study found that co-drugs synthesized from hydroquinone and tranexamic acid improved skin targeting and deposition, with reduced irritation and enhanced efficacy for treating hyperpigmentation.
6 citations
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March 2018 in “Journal of Medicinal Food” This study demonstrated that water-soluble peptides from egg yolk, termed "hair growth peptide," stimulated human hair follicle cell growth and improved hair growth in female pattern hair loss.
12 citations
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December 2003 in “Gene” This study characterized the Hoxc-13 gene from sheep wool follicles, noting its potential autoregulatory role and potential influence on skin function beyond hair keratin regulation.
3 citations
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November 2022 in “Molecules/Molecules online/Molecules annual” This study found that ingesting Lactobacillus paracasei HY7015 and Lycopus lucidus Turcz. extract promoted hair regrowth and follicle maturation in mice by enhancing cytoprotective effects and growth factor expression.
February 2026 in “International Journal of Molecular Sciences” This study found that 3-hydroxypropionic acid improved the function of hair follicle cells under oxidative stress, suggesting potential as a treatment for stress-related hair loss.
22 citations
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October 2004 in “Journal of Investigative Dermatology” This study identified the rough coat mutation in mice, but found that LOXL is not the causal gene, although its downregulation might contribute to related phenotypic changes.
11 citations
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January 2016 in “International Journal of Biological Macromolecules” This study found that enzymatic phosphorylation of hair keratin increased its capacity to adsorb cationic components like methylene blue and may have practical implications for hair care products.
161 citations
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June 1993 in “Journal of Biological Chemistry” This study suggests that human trichohyalin may function as a flexible rod linking keratin intermediate filaments and as a scaffold protein in hair follicle and epidermis cell envelopes.
July 2025 in “Journal of Investigative Dermatology” The new anti-aging ingredient improves skin hydration, elasticity, and reduces wrinkles.
4 citations
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December 1989 in “The Journal of Dermatology” This study suggests that the amino acid composition of fibrous proteins in normal human hair is similar to that of stratum corneum proteins, particularly in cysteine and glycine content.
November 2025 in “International Journal of Biological Macromolecules” This study introduced an eco-friendly enzymatic hair dyeing process utilizing laccase-catalyzed polymerization of hematoxylin, achieving intense, long-lasting color comparable to commercial dyes while enhancing hair strength and offering antioxidant and UV-shielding benefits.